दवाओं की अंतःक्रिया
Buprenorphine + Eluxadoline
गंभीरता: गंभीर
Buprenorphine and Eluxadoline: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Eluxadoline is a mu-opioid agonist used for diarrhea-predominant IBS and can cause severe constipation and pancreatitis-related events. Adding buprenorphine, which also slows gut transit, increases the risk of serious constipation and related complications.
इस इंटरैक्शन का सरल भाषा में अर्थ
Buprenorphine and Eluxadoline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Buprenorphine belongs to Musculoskeletal; Eluxadoline belongs to Gastrointestinal Tract.
ऐसा क्यों होता है
Additive opioid-receptor mediated reduction in gastrointestinal motility.
क्या करें
Avoid combining where possible; the eluxadoline label advises against use with other drugs that cause constipation. If both are required, monitor bowel function closely and stop eluxadoline if severe constipation develops.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Buprenorphine और Eluxadoline की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Buprenorphine के अन्य इंटरैक्शन
Eluxadoline के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Buprenorphine with Eluxadoline?
MediHelp rates the interaction as major. Buprenorphine and Eluxadoline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Eluxadoline is a mu-opioid agonist used for diarrhea-predominant IBS and can cause severe constipation and pancreatitis-related events. Adding buprenorphine, which also slows gut transit, increases the risk of serious constipation and related complications.
How serious is the interaction between Buprenorphine and Eluxadoline?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where possible; the eluxadoline label advises against use with other drugs that cause constipation. If both are required, monitor bowel function closely and stop eluxadoline if severe constipation develops.
What other medicines interact with Buprenorphine?
MediHelp also lists interactions of Buprenorphine with, for example, Alvimopan, Calcium / magnesium / potassium / sodium oxybates, Olanzapine / samidorphan. The full list is on the Buprenorphine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
