दवाओं की अंतःक्रिया
Buprenorphine + Esketamine
गंभीरता: गंभीर
Buprenorphine and Esketamine: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Opioids and esketamine both depress the CNS, and together they raise the risk of profound sedation and respiratory depression. Buprenorphine has a ceiling on respiratory effects, but the risk remains when combined with other depressants.
इस इंटरैक्शन का सरल भाषा में अर्थ
Buprenorphine and Esketamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Buprenorphine belongs to Musculoskeletal; Esketamine belongs to Central Nervous System.
ऐसा क्यों होता है
Additive CNS and respiratory depression via opioid receptor agonism and NMDA antagonism.
क्या करें
Monitor sedation, respiratory rate and oxygen saturation closely during and after esketamine administration, and use the lowest effective buprenorphine dose.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Buprenorphine और Esketamine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Esketamine के अन्य इंटरैक्शन
Buprenorphine के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Buprenorphine with Esketamine?
MediHelp rates the interaction as major. Buprenorphine and Esketamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Opioids and esketamine both depress the CNS, and together they raise the risk of profound sedation and respiratory depression. Buprenorphine has a ceiling on respiratory effects, but the risk remains when combined with other depressants.
How serious is the interaction between Buprenorphine and Esketamine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor sedation, respiratory rate and oxygen saturation closely during and after esketamine administration, and use the lowest effective buprenorphine dose.
What other medicines interact with Esketamine?
MediHelp also lists interactions of Esketamine with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Esketamine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
