दवाओं की अंतःक्रिया
Buprenorphine + Tranylcypromine
गंभीरता: निषिद्ध
Buprenorphine and Tranylcypromine: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Combining opioids with a nonselective MAO inhibitor has caused severe reactions such as hypotension, hyperthermia, profound sedation, serotonin toxicity and death. Buprenorphine labeling advises against use during or within 14 days of MAOI treatment.
इस इंटरैक्शन का सरल भाषा में अर्थ
Buprenorphine and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Buprenorphine belongs to Musculoskeletal; Tranylcypromine belongs to Central Nervous System.
ऐसा क्यों होता है
MAO inhibition may potentiate serotonergic and CNS-depressant effects of opioids; the exact mechanism with buprenorphine is not fully defined.
क्या करें
Do not use together; separate by at least 14 days after stopping tranylcypromine and choose a non-interacting analgesic.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Buprenorphine और Tranylcypromine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Buprenorphine के अन्य इंटरैक्शन
Tranylcypromine के अन्य इंटरैक्शन
- 5-HTP + Tranylcypromine निषिद्ध
- Amitriptyline + Tranylcypromine निषिद्ध
- Amoxapine + Tranylcypromine निषिद्ध
- Atomoxetine + Tranylcypromine निषिद्ध
- Benzphetamine + Tranylcypromine निषिद्ध
- Brimonidine + Tranylcypromine निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Buprenorphine with Tranylcypromine?
MediHelp rates the interaction as contraindicated. Buprenorphine and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Combining opioids with a nonselective MAO inhibitor has caused severe reactions such as hypotension, hyperthermia, profound sedation, serotonin toxicity and death. Buprenorphine labeling advises against use during or within 14 days of MAOI treatment.
How serious is the interaction between Buprenorphine and Tranylcypromine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; separate by at least 14 days after stopping tranylcypromine and choose a non-interacting analgesic.
What other medicines interact with Buprenorphine?
MediHelp also lists interactions of Buprenorphine with, for example, Alvimopan, Calcium / magnesium / potassium / sodium oxybates, Olanzapine / samidorphan. The full list is on the Buprenorphine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
