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दवाओं की अंतःक्रिया

Bupropion + Thioridazine

गंभीरता: निषिद्ध

Bupropion and Thioridazine: contraindicated interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Thioridazine is metabolised by CYP2D6, and bupropion is a strong inhibitor of this enzyme. Higher thioridazine levels can cause marked QT prolongation and torsades de pointes. Thioridazine labeling contraindicates drugs that inhibit its metabolism.

इस इंटरैक्शन का सरल भाषा में अर्थ

Bupropion and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Bupropion belongs to Central Nervous System; Thioridazine belongs to Central Nervous System.

साक्ष्य स्तर: High

ऐसा क्यों होता है

Bupropion inhibits CYP2D6, raising thioridazine levels and QT prolongation risk.

क्या करें

Do not combine; use an alternative antidepressant or antipsychotic. If exposure occurs, obtain an ECG and check potassium and magnesium.

फार्मासिस्ट से क्या पूछें

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Bupropion और Thioridazine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Bupropion with Thioridazine?

MediHelp rates the interaction as contraindicated. Bupropion and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Thioridazine is metabolised by CYP2D6, and bupropion is a strong inhibitor of this enzyme. Higher thioridazine levels can cause marked QT prolongation and torsades de pointes. Thioridazine labeling contraindicates drugs that inhibit its metabolism.

How serious is the interaction between Bupropion and Thioridazine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use an alternative antidepressant or antipsychotic. If exposure occurs, obtain an ECG and check potassium and magnesium.

What other medicines interact with Bupropion?

MediHelp also lists interactions of Bupropion with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Bupropion page.

MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर

MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।

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