दवाओं की अंतःक्रिया
Caplacizumab + Dabigatran etexilate
गंभीरता: गंभीर
Caplacizumab and Dabigatran etexilate: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Caplacizumab blocks von Willebrand factor-platelet binding and impairs primary hemostasis, and dabigatran adds anticoagulant effect. Together they increase the risk of serious bleeding.
इस इंटरैक्शन का सरल भाषा में अर्थ
Caplacizumab and Dabigatran etexilate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Caplacizumab belongs to Cardiovascular; Dabigatran etexilate belongs to Cardiovascular.
ऐसा क्यों होता है
Additive hemostatic impairment: antiplatelet-like vWF inhibition plus direct thrombin inhibition.
क्या करें
Avoid concurrent use where possible; if anticoagulation is essential, monitor closely for bleeding and consider holding dabigatran during caplacizumab treatment. Withhold both before invasive procedures per labeling.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Caplacizumab और Dabigatran etexilate की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Dabigatran etexilate के अन्य इंटरैक्शन
Caplacizumab के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Caplacizumab with Dabigatran etexilate?
MediHelp rates the interaction as major. Caplacizumab and Dabigatran etexilate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Caplacizumab blocks von Willebrand factor-platelet binding and impairs primary hemostasis, and dabigatran adds anticoagulant effect. Together they increase the risk of serious bleeding.
How serious is the interaction between Caplacizumab and Dabigatran etexilate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where possible; if anticoagulation is essential, monitor closely for bleeding and consider holding dabigatran during caplacizumab treatment. Withhold both before invasive procedures per labeling.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dabigatran etexilate page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
