दवाओं की अंतःक्रिया
Chenodeoxycholic acid + Cyclosporin
गंभीरता: गंभीर
Chenodeoxycholic acid and Cyclosporin: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Ciclosporin may inhibit CYP27A1 and reduce bile acid synthesis, which may blunt the effect of chenodeoxycholic acid in conditions like cerebrotendinous xanthomatosis. Disease control could worsen.
इस इंटरैक्शन का सरल भाषा में अर्थ
Chenodeoxycholic acid and Cyclosporin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Chenodeoxycholic acid belongs to Gastrointestinal Tract; Cyclosporin belongs to Miscellaneous.
ऐसा क्यों होता है
Inhibition of CYP27A1 by ciclosporin reduces bile acid synthesis and alters pharmacodynamic response.
क्या करें
Avoid if possible; otherwise monitor serum bile alcohols and adjust the chenodeoxycholic acid dose.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Chenodeoxycholic acid और Cyclosporin की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Chenodeoxycholic acid के अन्य इंटरैक्शन
Cyclosporin के अन्य इंटरैक्शन
- Adenovirus types 4 and 7 live + Cyclosporin निषिद्ध
- Aliskiren + Cyclosporin निषिद्ध
- Bcg vaccine live + Cyclosporin निषिद्ध
- Bosentan + Cyclosporin निषिद्ध
- Cidofovir + Cyclosporin निषिद्ध
- Cyclosporin + Dengue vaccine निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Chenodeoxycholic acid with Cyclosporin?
MediHelp rates the interaction as major. Chenodeoxycholic acid and Cyclosporin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ciclosporin may inhibit CYP27A1 and reduce bile acid synthesis, which may blunt the effect of chenodeoxycholic acid in conditions like cerebrotendinous xanthomatosis. Disease control could worsen.
How serious is the interaction between Chenodeoxycholic acid and Cyclosporin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible; otherwise monitor serum bile alcohols and adjust the chenodeoxycholic acid dose.
What other medicines interact with Chenodeoxycholic acid?
MediHelp also lists interactions of Chenodeoxycholic acid with, for example, Sirolimus, Aluminum hydroxide, Colestipol. The full list is on the Chenodeoxycholic acid page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
