दवाओं की अंतःक्रिया
Chlorpropamide + Ofloxacin
गंभीरता: गंभीर
Chlorpropamide and Ofloxacin: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Ofloxacin can cause severe hypoglycemia or hyperglycemia in patients taking sulfonylureas. Chlorpropamide has a long half-life, so hypoglycemia may be prolonged and may need hospital treatment.
इस इंटरैक्शन का सरल भाषा में अर्थ
Chlorpropamide and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Chlorpropamide belongs to Endocrine; Ofloxacin belongs to Anti Bacterial.
ऐसा क्यों होता है
Fluoroquinolones stimulate insulin release by blocking pancreatic beta-cell ATP-sensitive potassium channels, adding to the sulfonylurea effect.
क्या करें
Monitor blood glucose closely during ofloxacin therapy and consider reducing the sulfonylurea dose. Teach patients about hypoglycemia and use an alternative antibiotic in high-risk patients such as the elderly or those with renal impairment.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Chlorpropamide और Ofloxacin की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Ofloxacin के अन्य इंटरैक्शन
- Ofloxacin + Thioridazine निषिद्ध
- Adagrasib + Ofloxacin गंभीर
- Amiodarone + Ofloxacin गंभीर
- Amisulpride + Ofloxacin गंभीर
- Anagrelide + Ofloxacin गंभीर
- Arsenic trioxide + Ofloxacin गंभीर
Chlorpropamide के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Chlorpropamide with Ofloxacin?
MediHelp rates the interaction as major. Chlorpropamide and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ofloxacin can cause severe hypoglycemia or hyperglycemia in patients taking sulfonylureas. Chlorpropamide has a long half-life, so hypoglycemia may be prolonged and may need hospital treatment.
How serious is the interaction between Chlorpropamide and Ofloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose closely during ofloxacin therapy and consider reducing the sulfonylurea dose. Teach patients about hypoglycemia and use an alternative antibiotic in high-risk patients such as the elderly or those with renal impairment.
What other medicines interact with Ofloxacin?
MediHelp also lists interactions of Ofloxacin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Ofloxacin page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
