दवाओं की अंतःक्रिया
Cimetidine + Epirubicin
गंभीरता: गंभीर
Cimetidine and Epirubicin: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Cimetidine has been shown to increase epirubicin exposure, which can intensify myelosuppression and cardiotoxicity. Epirubicin labeling advises against concurrent use.
इस इंटरैक्शन का सरल भाषा में अर्थ
Cimetidine and Epirubicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cimetidine belongs to Gastrointestinal Tract; Epirubicin belongs to Oncology.
ऐसा क्यों होता है
Cimetidine reduces the hepatic metabolism and clearance of epirubicin.
क्या करें
Stop cimetidine before and during epirubicin treatment and use an alternative such as famotidine or a proton pump inhibitor. Monitor blood counts and cardiac function.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Cimetidine और Epirubicin की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Cimetidine के अन्य इंटरैक्शन
- Cimetidine + Dofetilide निषिद्ध
- Cimetidine + Fezolinetant निषिद्ध
- Alfentanil + Cimetidine गंभीर
- Atazanavir + Cimetidine गंभीर
- Carmustine + Cimetidine गंभीर
- Cimetidine + Citalopram गंभीर
Epirubicin के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Cimetidine with Epirubicin?
MediHelp rates the interaction as major. Cimetidine and Epirubicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cimetidine has been shown to increase epirubicin exposure, which can intensify myelosuppression and cardiotoxicity. Epirubicin labeling advises against concurrent use.
How serious is the interaction between Cimetidine and Epirubicin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Stop cimetidine before and during epirubicin treatment and use an alternative such as famotidine or a proton pump inhibitor. Monitor blood counts and cardiac function.
What other medicines interact with Cimetidine?
MediHelp also lists interactions of Cimetidine with, for example, Dofetilide, Fezolinetant, Alfentanil. The full list is on the Cimetidine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
