दवाओं की अंतःक्रिया
Citalopram + Phenelzine
गंभीरता: निषिद्ध
Citalopram and Phenelzine: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Citalopram raises synaptic serotonin by blocking reuptake, and phenelzine (an irreversible non-selective MAO inhibitor) prevents its breakdown. Serotonin syndrome with agitation, hyperthermia, clonus and autonomic instability can develop, sometimes fatally.
इस इंटरैक्शन का सरल भाषा में अर्थ
Citalopram and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Citalopram belongs to Central Nervous System; Phenelzine belongs to Central Nervous System.
ऐसा क्यों होता है
Serotonin reuptake inhibition combined with MAO inhibition causes excess serotonergic activity
क्या करें
Contraindicated. Wait at least 14 days after stopping phenelzine before starting the other drug; allow at least 2 weeks between stopping an irreversible MAOI and starting citalopram, and about a week the other way round.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Citalopram और Phenelzine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Citalopram के अन्य इंटरैक्शन
- Cisapride + Citalopram निषिद्ध
- Citalopram + Dronedarone निषिद्ध
- Citalopram + Escitalopram निषिद्ध
- Citalopram + Isocarboxazid निषिद्ध
- Citalopram + Methylene blue निषिद्ध
- Citalopram + Pimozide निषिद्ध
Phenelzine के अन्य इंटरैक्शन
- 5-HTP + Phenelzine निषिद्ध
- Amitriptyline + Phenelzine निषिद्ध
- Amoxapine + Phenelzine निषिद्ध
- Atomoxetine + Phenelzine निषिद्ध
- Benzphetamine + Phenelzine निषिद्ध
- Brimonidine + Phenelzine निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Citalopram with Phenelzine?
MediHelp rates the interaction as contraindicated. Citalopram and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Citalopram raises synaptic serotonin by blocking reuptake, and phenelzine (an irreversible non-selective MAO inhibitor) prevents its breakdown. Serotonin syndrome with agitation, hyperthermia, clonus and autonomic instability can develop, sometimes fatally.
How serious is the interaction between Citalopram and Phenelzine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Contraindicated. Wait at least 14 days after stopping phenelzine before starting the other drug; allow at least 2 weeks between stopping an irreversible MAOI and starting citalopram, and about a week the other way round.
What other medicines interact with Citalopram?
MediHelp also lists interactions of Citalopram with, for example, Cisapride, Dronedarone, Escitalopram. The full list is on the Citalopram page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
