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दवाओं की अंतःक्रिया

Clomipramine + Isocarboxazid

गंभीरता: निषिद्ध

Clomipramine and Isocarboxazid: contraindicated interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Clomipramine is a potent serotonin and noradrenaline reuptake inhibitor, and isocarboxazid (an irreversible non-selective MAO inhibitor) blocks monoamine breakdown. Serotonin syndrome and hypertensive crisis are the main dangers.

इस इंटरैक्शन का सरल भाषा में अर्थ

Clomipramine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Clomipramine belongs to Central Nervous System; Isocarboxazid belongs to Central Nervous System.

साक्ष्य स्तर: High

ऐसा क्यों होता है

Monoamine reuptake inhibition plus MAO inhibition

क्या करें

Do not use together. Wait at least 14 days after stopping isocarboxazid before starting the other drug; leave about 2 weeks after stopping clomipramine before starting an irreversible MAOI.

फार्मासिस्ट से क्या पूछें

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Clomipramine और Isocarboxazid की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Clomipramine with Isocarboxazid?

MediHelp rates the interaction as contraindicated. Clomipramine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Clomipramine is a potent serotonin and noradrenaline reuptake inhibitor, and isocarboxazid (an irreversible non-selective MAO inhibitor) blocks monoamine breakdown. Serotonin syndrome and hypertensive crisis are the main dangers.

How serious is the interaction between Clomipramine and Isocarboxazid?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together. Wait at least 14 days after stopping isocarboxazid before starting the other drug; leave about 2 weeks after stopping clomipramine before starting an irreversible MAOI.

What other medicines interact with Clomipramine?

MediHelp also lists interactions of Clomipramine with, for example, Arsenic trioxide, Dofetilide, Droperidol. The full list is on the Clomipramine page.

MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर

MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।

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