दवाओं की अंतःक्रिया
Contrast media + Dapagliflozin-metformin
गंभीरता: गंभीर
Contrast media and Dapagliflozin-metformin: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Iodinated contrast can cause acute kidney injury, and metformin is eliminated unchanged by the kidneys. Reduced clearance leads to metformin accumulation and raises the risk of lactic acidosis, and dapagliflozin's volume-depleting effect may add to renal risk.
इस इंटरैक्शन का सरल भाषा में अर्थ
Contrast media and Dapagliflozin-metformin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Contrast-induced reduction in renal function decreases renal elimination of metformin, causing accumulation.
क्या करें
Hold metformin at the time of or before the procedure in patients with reduced eGFR, liver disease, alcoholism, heart failure or intra-arterial contrast. Re-check renal function about 48 hours afterward and restart only if it is stable.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Contrast media और Dapagliflozin-metformin की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Dapagliflozin-metformin के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Contrast media with Dapagliflozin-metformin?
MediHelp rates the interaction as major. Contrast media and Dapagliflozin-metformin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Iodinated contrast can cause acute kidney injury, and metformin is eliminated unchanged by the kidneys. Reduced clearance leads to metformin accumulation and raises the risk of lactic acidosis, and dapagliflozin's volume-depleting effect may add to renal risk.
How serious is the interaction between Contrast media and Dapagliflozin-metformin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Hold metformin at the time of or before the procedure in patients with reduced eGFR, liver disease, alcoholism, heart failure or intra-arterial contrast. Re-check renal function about 48 hours afterward and restart only if it is stable.
What other medicines interact with Dapagliflozin-metformin?
MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Diatrizoate, Diatrizoate meglumine / diatrizoate, Ethanol. The full list is on the Dapagliflozin-metformin page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
