दवाओं की अंतःक्रिया
Cyclobenzaprine + Selegiline transdermal
गंभीरता: निषिद्ध
Cyclobenzaprine and Selegiline transdermal: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Cyclobenzaprine is structurally related to tricyclic antidepressants, and its labeling contraindicates use with or within 14 days of MAO inhibitors. Combining it with selegiline, an MAO inhibitor, can cause serotonin syndrome, hypertensive crisis, severe convulsions, and death.
इस इंटरैक्शन का सरल भाषा में अर्थ
Cyclobenzaprine and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
ऐसा क्यों होता है
Inhibition of MAO by selegiline combined with the serotonergic and noradrenergic reuptake effects of cyclobenzaprine leads to excess monoamine activity.
क्या करें
Avoid the combination and choose a non-serotonergic muscle relaxant. Allow a washout of at least 14 days after stopping an MAO inhibitor before starting cyclobenzaprine.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Cyclobenzaprine और Selegiline transdermal की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Cyclobenzaprine के अन्य इंटरैक्शन
- Cyclobenzaprine + Isocarboxazid निषिद्ध
- Cyclobenzaprine + Linezolid निषिद्ध
- Cyclobenzaprine + Phenelzine निषिद्ध
- Cyclobenzaprine + Safinamide निषिद्ध
- Cyclobenzaprine + Selegiline निषिद्ध
- Cyclobenzaprine + Tranylcypromine निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Cyclobenzaprine with Selegiline transdermal?
MediHelp rates the interaction as contraindicated. Cyclobenzaprine and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Cyclobenzaprine is structurally related to tricyclic antidepressants, and its labeling contraindicates use with or within 14 days of MAO inhibitors. Combining it with selegiline, an MAO inhibitor, can cause serotonin syndrome, hypertensive crisis, severe convulsions, and death.
How serious is the interaction between Cyclobenzaprine and Selegiline transdermal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose a non-serotonergic muscle relaxant. Allow a washout of at least 14 days after stopping an MAO inhibitor before starting cyclobenzaprine.
What other medicines interact with Cyclobenzaprine?
MediHelp also lists interactions of Cyclobenzaprine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Cyclobenzaprine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
