दवाओं की अंतःक्रिया
Cyclosporine + Etoposide
गंभीरता: गंभीर
Cyclosporine and Etoposide: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Cyclosporine inhibits CYP3A4 and P-glycoprotein and can markedly raise etoposide exposure. This may cause more severe myelosuppression and mucositis, and cyclosporine's own immunosuppression adds to the risk of infection.
इस इंटरैक्शन का सरल भाषा में अर्थ
Cyclosporine and Etoposide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Inhibition of P-gp efflux and CYP3A4 metabolism of etoposide by cyclosporine.
क्या करें
Reduce the etoposide dose when given with cyclosporine and monitor blood counts closely. Watch for infection and mucositis.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Cyclosporine और Etoposide की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Etoposide के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Cyclosporine with Etoposide?
MediHelp rates the interaction as major. Cyclosporine and Etoposide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cyclosporine inhibits CYP3A4 and P-glycoprotein and can markedly raise etoposide exposure. This may cause more severe myelosuppression and mucositis, and cyclosporine's own immunosuppression adds to the risk of infection.
How serious is the interaction between Cyclosporine and Etoposide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Reduce the etoposide dose when given with cyclosporine and monitor blood counts closely. Watch for infection and mucositis.
What other medicines interact with Etoposide?
MediHelp also lists interactions of Etoposide with, for example, Adenovirus types 4 and 7 live, Pentostatin, Cyclosporin. The full list is on the Etoposide page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
