दवाओं की अंतःक्रिया
Cyclosporine + Red yeast rice
गंभीरता: गंभीर
Cyclosporine and Red yeast rice: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Monacolin K in red yeast rice is lovastatin, and cyclosporine markedly raises lovastatin exposure through CYP3A4 and OATP1B1 inhibition. This increases the risk of myopathy and rhabdomyolysis, particularly in transplant recipients.
इस इंटरैक्शन का सरल भाषा में अर्थ
Cyclosporine and Red yeast rice can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Cyclosporine inhibits CYP3A4 and hepatic OATP uptake, increasing monacolin K (lovastatin) exposure.
क्या करें
Avoid red yeast rice in patients on cyclosporine and treat dyslipidemia with a statin and dose appropriate for use with cyclosporine. Monitor for muscle symptoms and creatine kinase.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Cyclosporine और Red yeast rice की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Red yeast rice के अन्य इंटरैक्शन
- Red yeast rice + Ritonavir निषिद्ध
- Red yeast rice + Saquinavir निषिद्ध
- Red yeast rice + Tipranavir निषिद्ध
- Atazanavir + Red yeast rice गंभीर
- Atorvastatin + Red yeast rice गंभीर
- Conivaptan + Red yeast rice गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Cyclosporine with Red yeast rice?
MediHelp rates the interaction as major. Cyclosporine and Red yeast rice can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Monacolin K in red yeast rice is lovastatin, and cyclosporine markedly raises lovastatin exposure through CYP3A4 and OATP1B1 inhibition. This increases the risk of myopathy and rhabdomyolysis, particularly in transplant recipients.
How serious is the interaction between Cyclosporine and Red yeast rice?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid red yeast rice in patients on cyclosporine and treat dyslipidemia with a statin and dose appropriate for use with cyclosporine. Monitor for muscle symptoms and creatine kinase.
What other medicines interact with Red yeast rice?
MediHelp also lists interactions of Red yeast rice with, for example, Ritonavir, Saquinavir, Tipranavir. The full list is on the Red yeast rice page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
