दवाओं की अंतःक्रिया
Dextroamphetamine + Selegiline
गंभीरता: निषिद्ध
Dextroamphetamine and Selegiline: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Selegiline inhibits catecholamine breakdown and enlarges neuronal norepinephrine stores, and dextroamphetamine releases norepinephrine and dopamine from nerve terminals. The result can be a hypertensive crisis with severe headache, arrhythmia, hyperpyrexia and intracranial haemorrhage.
इस इंटरैक्शन का सरल भाषा में अर्थ
Dextroamphetamine and Selegiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dextroamphetamine belongs to Central Nervous System; Selegiline belongs to Central Nervous System.
ऐसा क्यों होता है
MAO inhibition plus indirect sympathomimetic norepinephrine release -> exaggerated pressor response
क्या करें
Do not give dextroamphetamine during or within 14 days of an MAO inhibitor, and leave at least 14 days after stopping the stimulant before starting the MAO inhibitor.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Dextroamphetamine और Selegiline की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Dextroamphetamine के अन्य इंटरैक्शन
- Dextroamphetamine + Isocarboxazid निषिद्ध
- Dextroamphetamine + Linezolid निषिद्ध
- Dextroamphetamine + Methylene blue निषिद्ध
- Dextroamphetamine + Phenelzine निषिद्ध
- Dextroamphetamine + Rasagiline निषिद्ध
- Dextroamphetamine + Safinamide निषिद्ध
Selegiline के अन्य इंटरैक्शन
- Amitriptyline + Selegiline निषिद्ध
- Amoxapine + Selegiline निषिद्ध
- Atomoxetine + Selegiline निषिद्ध
- Benzphetamine + Selegiline निषिद्ध
- Brimonidine + Selegiline निषिद्ध
- Buprenorphine long-acting + Selegiline निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Dextroamphetamine with Selegiline?
MediHelp rates the interaction as contraindicated. Dextroamphetamine and Selegiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Selegiline inhibits catecholamine breakdown and enlarges neuronal norepinephrine stores, and dextroamphetamine releases norepinephrine and dopamine from nerve terminals. The result can be a hypertensive crisis with severe headache, arrhythmia, hyperpyrexia and intracranial haemorrhage.
How serious is the interaction between Dextroamphetamine and Selegiline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give dextroamphetamine during or within 14 days of an MAO inhibitor, and leave at least 14 days after stopping the stimulant before starting the MAO inhibitor.
What other medicines interact with Dextroamphetamine?
MediHelp also lists interactions of Dextroamphetamine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Dextroamphetamine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
