दवाओं की अंतःक्रिया
Didanosine + Hydroxyurea
गंभीरता: निषिद्ध
Didanosine and Hydroxyurea: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Hydroxyurea combined with didanosine has caused pancreatitis, hepatotoxicity including fatal hepatic failure, and peripheral neuropathy in HIV patients. The overlapping toxicities make the combination dangerous.
इस इंटरैक्शन का सरल भाषा में अर्थ
Didanosine and Hydroxyurea are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Didanosine belongs to Anti Virals; Hydroxyurea belongs to Miscellaneous.
ऐसा क्यों होता है
Additive pancreatic, hepatic and neurotoxicity; the exact mechanism is not fully established.
क्या करें
Do not combine; choose a different antiretroviral. If exposure has occurred, monitor for pancreatitis, liver injury and neuropathy and stop the agents if signs appear.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Didanosine और Hydroxyurea की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Didanosine के अन्य इंटरैक्शन
Hydroxyurea के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Didanosine with Hydroxyurea?
MediHelp rates the interaction as contraindicated. Didanosine and Hydroxyurea are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Hydroxyurea combined with didanosine has caused pancreatitis, hepatotoxicity including fatal hepatic failure, and peripheral neuropathy in HIV patients. The overlapping toxicities make the combination dangerous.
How serious is the interaction between Didanosine and Hydroxyurea?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; choose a different antiretroviral. If exposure has occurred, monitor for pancreatitis, liver injury and neuropathy and stop the agents if signs appear.
What other medicines interact with Didanosine?
MediHelp also lists interactions of Didanosine with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Hydroxycarbamide, Ribavirin. The full list is on the Didanosine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
