दवाओं की अंतःक्रिया
Dihydroergotamine intranasal + Phenylephrine
गंभीरता: गंभीर
Dihydroergotamine intranasal and Phenylephrine: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Phenylephrine is an alpha-1 agonist vasoconstrictor and dihydroergotamine also constricts blood vessels, so combined use can produce marked vasoconstriction and a rise in blood pressure. Peripheral or cerebral ischemia is possible, especially with systemic phenylephrine exposure.
इस इंटरैक्शन का सरल भाषा में अर्थ
Dihydroergotamine intranasal and Phenylephrine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Additive pharmacodynamic vasoconstriction through alpha-adrenergic agonism and ergot-mediated serotonergic and adrenergic vascular effects.
क्या करें
Avoid systemic or repeated use of phenylephrine with dihydroergotamine; choose a non-vasoconstrictor alternative. If unavoidable, monitor blood pressure and watch for ischemic symptoms.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Dihydroergotamine intranasal और Phenylephrine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Phenylephrine के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Dihydroergotamine intranasal with Phenylephrine?
MediHelp rates the interaction as major. Dihydroergotamine intranasal and Phenylephrine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Phenylephrine is an alpha-1 agonist vasoconstrictor and dihydroergotamine also constricts blood vessels, so combined use can produce marked vasoconstriction and a rise in blood pressure. Peripheral or cerebral ischemia is possible, especially with systemic phenylephrine exposure.
How serious is the interaction between Dihydroergotamine intranasal and Phenylephrine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic or repeated use of phenylephrine with dihydroergotamine; choose a non-vasoconstrictor alternative. If unavoidable, monitor blood pressure and watch for ischemic symptoms.
What other medicines interact with Phenylephrine?
MediHelp also lists interactions of Phenylephrine with, for example, Isocarboxazid, Phenelzine, Tranylcypromine. The full list is on the Phenylephrine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
