दवाओं की अंतःक्रिया
Dobutamine + Isocarboxazid
गंभीरता: गंभीर
Dobutamine and Isocarboxazid: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Inhibition of MAO slows catecholamine metabolism and enlarges neuronal stores, and dobutamine is a catecholamine inotrope with beta-1 agonist and some alpha activity. The pressor and chronotropic response to dobutamine can therefore be exaggerated, with severe hypertension, headache and arrhythmia.
इस इंटरैक्शन का सरल भाषा में अर्थ
Dobutamine and Isocarboxazid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dobutamine belongs to Cardiovascular; Isocarboxazid belongs to Central Nervous System.
ऐसा क्यों होता है
Reduced catecholamine degradation (MAO inhibition) with sympathomimetic stimulation
क्या करें
Avoid where possible; if dobutamine is required in a patient taking isocarboxazid, start at a markedly reduced dose and titrate against continuous blood-pressure and ECG monitoring.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Dobutamine और Isocarboxazid की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Dobutamine के अन्य इंटरैक्शन
Isocarboxazid के अन्य इंटरैक्शन
- 5-HTP + Isocarboxazid निषिद्ध
- Amitriptyline + Isocarboxazid निषिद्ध
- Amobarbital + Isocarboxazid निषिद्ध
- Amoxapine + Isocarboxazid निषिद्ध
- Apraclonidine + Isocarboxazid निषिद्ध
- Atomoxetine + Isocarboxazid निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Dobutamine with Isocarboxazid?
MediHelp rates the interaction as major. Dobutamine and Isocarboxazid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Inhibition of MAO slows catecholamine metabolism and enlarges neuronal stores, and dobutamine is a catecholamine inotrope with beta-1 agonist and some alpha activity. The pressor and chronotropic response to dobutamine can therefore be exaggerated, with severe hypertension, headache and arrhythmia.
How serious is the interaction between Dobutamine and Isocarboxazid?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid where possible; if dobutamine is required in a patient taking isocarboxazid, start at a markedly reduced dose and titrate against continuous blood-pressure and ECG monitoring.
What other medicines interact with Dobutamine?
MediHelp also lists interactions of Dobutamine with, for example, Budesonide-formoterol, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Dobutamine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
