दवाओं की अंतःक्रिया
Ethinyl estradiol-levonorgestrel + Ombitasvir / paritaprevir / ritonavir and dasabuvir
गंभीरता: निषिद्ध
Ethinyl estradiol-levonorgestrel and Ombitasvir / paritaprevir / ritonavir and dasabuvir: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Coadministration of ethinyl estradiol-containing products with this HCV regimen has produced marked ALT elevations in clinical trials. The risk of liver injury makes the combination unsuitable. Ritonavir may also reduce contraceptive hormone exposure.
इस इंटरैक्शन का सरल भाषा में अर्थ
Ethinyl estradiol-levonorgestrel and Ombitasvir / paritaprevir / ritonavir and dasabuvir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
ऐसा क्यों होता है
The mechanism of the ALT elevation is not established; ritonavir may also alter estrogen metabolism.
क्या करें
Avoid ethinyl estradiol-containing contraceptives before and during this regimen. Switch to a progestin-only or non-hormonal method and restart estrogen only after the regimen has been completed, as advised in the labeling.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Ethinyl estradiol-levonorgestrel और Ombitasvir / paritaprevir / ritonavir and dasabuvir की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Ethinyl estradiol-levonorgestrel के अन्य इंटरैक्शन
- Ethinyl estradiol-levonorgestrel + Fezolinetant निषिद्ध
- Ethinyl estradiol-levonorgestrel + Tranexamic acid निषिद्ध
- Aminocaproic acid + Ethinyl estradiol-levonorgestrel गंभीर
- Amobarbital + Ethinyl estradiol-levonorgestrel गंभीर
- Anastrozole + Ethinyl estradiol-levonorgestrel गंभीर
- Antithrombin alfa + Ethinyl estradiol-levonorgestrel गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Ethinyl estradiol-levonorgestrel with Ombitasvir / paritaprevir / ritonavir and dasabuvir?
MediHelp rates the interaction as contraindicated. Ethinyl estradiol-levonorgestrel and Ombitasvir / paritaprevir / ritonavir and dasabuvir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Coadministration of ethinyl estradiol-containing products with this HCV regimen has produced marked ALT elevations in clinical trials. The risk of liver injury makes the combination unsuitable. Ritonavir may also reduce contraceptive hormone exposure.
How serious is the interaction between Ethinyl estradiol-levonorgestrel and Ombitasvir / paritaprevir / ritonavir and dasabuvir?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ethinyl estradiol-containing contraceptives before and during this regimen. Switch to a progestin-only or non-hormonal method and restart estrogen only after the regimen has been completed, as advised in the labeling.
What other medicines interact with Ethinyl estradiol-levonorgestrel?
MediHelp also lists interactions of Ethinyl estradiol-levonorgestrel with, for example, Fezolinetant, Tranexamic acid, Aminocaproic acid. The full list is on the Ethinyl estradiol-levonorgestrel page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
