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दवाओं की अंतःक्रिया

Fentanyl + Olanzapine / samidorphan

गंभीरता: निषिद्ध

Fentanyl and Olanzapine / samidorphan: contraindicated interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Samidorphan blocks opioid receptors, reducing fentanyl's analgesic effect and potentially precipitating withdrawal in opioid-dependent patients. Attempts to overcome the blockade with higher opioid doses risk overdose.

इस इंटरैक्शन का सरल भाषा में अर्थ

Fentanyl and Olanzapine / samidorphan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

साक्ष्य स्तर: High

ऐसा क्यों होता है

Samidorphan is a mu-opioid receptor antagonist that opposes fentanyl's agonist effects.

क्या करें

Ensure an opioid-free interval of at least 7 days for short-acting and 14 days for long-acting opioids before starting. Use an alternative antipsychotic in patients who need opioids.

फार्मासिस्ट से क्या पूछें

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Fentanyl और Olanzapine / samidorphan की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Fentanyl with Olanzapine / samidorphan?

MediHelp rates the interaction as contraindicated. Fentanyl and Olanzapine / samidorphan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Samidorphan blocks opioid receptors, reducing fentanyl's analgesic effect and potentially precipitating withdrawal in opioid-dependent patients. Attempts to overcome the blockade with higher opioid doses risk overdose.

How serious is the interaction between Fentanyl and Olanzapine / samidorphan?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ensure an opioid-free interval of at least 7 days for short-acting and 14 days for long-acting opioids before starting. Use an alternative antipsychotic in patients who need opioids.

What other medicines interact with Fentanyl?

MediHelp also lists interactions of Fentanyl with, for example, Alvimopan, Isocarboxazid, Phenelzine. The full list is on the Fentanyl page.

MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर

MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।

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