दवाओं की अंतःक्रिया
Fluoxetine + Rasagiline
गंभीरता: निषिद्ध
Fluoxetine and Rasagiline: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Combining an SSRI with a monoamine oxidase B inhibitor can cause serotonin syndrome, with severe hyperthermia, rigidity and autonomic instability reported with antidepressants and rasagiline. Fluoxetine's very long-acting metabolite prolongs the risk after it is stopped.
इस इंटरैक्शन का सरल भाषा में अर्थ
Fluoxetine and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Fluoxetine belongs to Central Nervous System; Rasagiline belongs to Central Nervous System.
ऐसा क्यों होता है
Reduced serotonin breakdown from MAO inhibition combined with serotonin reuptake inhibition produces excess serotonergic activity.
क्या करें
Do not co-administer; rasagiline labeling advises waiting about five weeks after stopping fluoxetine before starting rasagiline, and at least 14 days after stopping rasagiline before starting fluoxetine. Treat suspected serotonin syndrome by stopping both drugs and giving supportive care.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Fluoxetine और Rasagiline की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Fluoxetine के अन्य इंटरैक्शन
- Fluoxetine + Isocarboxazid निषिद्ध
- Fluoxetine + Mavacamten निषिद्ध
- Fluoxetine + Methylene blue निषिद्ध
- Fluoxetine + Phenelzine निषिद्ध
- Fluoxetine + Pimozide निषिद्ध
- Fluoxetine + Selegiline निषिद्ध
Rasagiline के अन्य इंटरैक्शन
- Atomoxetine + Rasagiline निषिद्ध
- Brimonidine + Rasagiline निषिद्ध
- Bupropion-naltrexone + Rasagiline निषिद्ध
- Bupropion + Rasagiline निषिद्ध
- Clomipramine + Rasagiline निषिद्ध
- Desvenlafaxine + Rasagiline निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Fluoxetine with Rasagiline?
MediHelp rates the interaction as contraindicated. Fluoxetine and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Combining an SSRI with a monoamine oxidase B inhibitor can cause serotonin syndrome, with severe hyperthermia, rigidity and autonomic instability reported with antidepressants and rasagiline. Fluoxetine's very long-acting metabolite prolongs the risk after it is stopped.
How serious is the interaction between Fluoxetine and Rasagiline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; rasagiline labeling advises waiting about five weeks after stopping fluoxetine before starting rasagiline, and at least 14 days after stopping rasagiline before starting fluoxetine. Treat suspected serotonin syndrome by stopping both drugs and giving supportive care.
What other medicines interact with Fluoxetine?
MediHelp also lists interactions of Fluoxetine with, for example, Isocarboxazid, Mavacamten, Methylene blue. The full list is on the Fluoxetine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
