दवाओं की अंतःक्रिया
Fosinopril-hydrochlorothiazide + Sacubitril / valsartan
गंभीरता: निषिद्ध
Fosinopril-hydrochlorothiazide and Sacubitril / valsartan: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Concurrent ACE inhibition and neprilysin inhibition substantially increases the risk of angioedema, which may involve the airway. Additive RAS blockade also raises hypotension and hyperkalemia risk.
इस इंटरैक्शन का सरल भाषा में अर्थ
Fosinopril-hydrochlorothiazide and Sacubitril / valsartan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
ऐसा क्यों होता है
Combined ACE and neprilysin inhibition reduces bradykinin degradation, causing excess bradykinin and angioedema.
क्या करें
Never coadminister; leave at least 36 hours between stopping fosinopril and starting sacubitril/valsartan, or the reverse.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Fosinopril-hydrochlorothiazide और Sacubitril / valsartan की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Fosinopril-hydrochlorothiazide के अन्य इंटरैक्शन
- Aliskiren + Fosinopril-hydrochlorothiazide निषिद्ध
- Dofetilide + Fosinopril-hydrochlorothiazide निषिद्ध
- Fosinopril-hydrochlorothiazide + Protein a column निषिद्ध
- Aldesleukin + Fosinopril-hydrochlorothiazide गंभीर
- Amifostine + Fosinopril-hydrochlorothiazide गंभीर
- Amiloride + Fosinopril-hydrochlorothiazide गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Fosinopril-hydrochlorothiazide with Sacubitril / valsartan?
MediHelp rates the interaction as contraindicated. Fosinopril-hydrochlorothiazide and Sacubitril / valsartan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Concurrent ACE inhibition and neprilysin inhibition substantially increases the risk of angioedema, which may involve the airway. Additive RAS blockade also raises hypotension and hyperkalemia risk.
How serious is the interaction between Fosinopril-hydrochlorothiazide and Sacubitril / valsartan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Never coadminister; leave at least 36 hours between stopping fosinopril and starting sacubitril/valsartan, or the reverse.
What other medicines interact with Fosinopril-hydrochlorothiazide?
MediHelp also lists interactions of Fosinopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Fosinopril-hydrochlorothiazide page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
