दवाओं की अंतःक्रिया
Ganciclovir + Imipenem / cilastatin
गंभीरता: गंभीर
Ganciclovir and Imipenem / cilastatin: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Generalized seizures have been reported in patients given ganciclovir together with imipenem/cilastatin. Imipenem can lower the seizure threshold, and the combination appears to add to that risk.
इस इंटरैक्शन का सरल भाषा में अर्थ
Ganciclovir and Imipenem / cilastatin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Probable additive lowering of the seizure threshold; the exact mechanism is not established.
क्या करें
Avoid the combination unless the benefit clearly outweighs the risk, and consider a non-carbapenem antibiotic. If it must be used, adjust doses for renal function and monitor for neurological symptoms.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Ganciclovir और Imipenem / cilastatin की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Ganciclovir के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Ganciclovir with Imipenem / cilastatin?
MediHelp rates the interaction as major. Ganciclovir and Imipenem / cilastatin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Generalized seizures have been reported in patients given ganciclovir together with imipenem/cilastatin. Imipenem can lower the seizure threshold, and the combination appears to add to that risk.
How serious is the interaction between Ganciclovir and Imipenem / cilastatin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination unless the benefit clearly outweighs the risk, and consider a non-carbapenem antibiotic. If it must be used, adjust doses for renal function and monitor for neurological symptoms.
What other medicines interact with Ganciclovir?
MediHelp also lists interactions of Ganciclovir with, for example, Bacitracin, Cilastatin-imipenem, Didanosine. The full list is on the Ganciclovir page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
