दवाओं की अंतःक्रिया
Gliclazide + Sulfamethoxazole
गंभीरता: गंभीर
Gliclazide and Sulfamethoxazole: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Sulfamethoxazole, usually given as co-trimoxazole, can enhance the glucose-lowering effect of sulfonylureas and has been linked to serious hypoglycemia. Elderly patients and those with kidney disease are particularly vulnerable.
इस इंटरैक्शन का सरल भाषा में अर्थ
Gliclazide and Sulfamethoxazole can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Sulfamethoxazole inhibits CYP2C9, which metabolizes the sulfonylurea, and may displace it from protein binding.
क्या करें
Monitor blood glucose closely, particularly in the first days of therapy, and lower the gliclazide dose if needed; consider an alternative antibiotic in high-risk patients.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Gliclazide और Sulfamethoxazole की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Gliclazide के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Gliclazide with Sulfamethoxazole?
MediHelp rates the interaction as major. Gliclazide and Sulfamethoxazole can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Sulfamethoxazole, usually given as co-trimoxazole, can enhance the glucose-lowering effect of sulfonylureas and has been linked to serious hypoglycemia. Elderly patients and those with kidney disease are particularly vulnerable.
How serious is the interaction between Gliclazide and Sulfamethoxazole?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose closely, particularly in the first days of therapy, and lower the gliclazide dose if needed; consider an alternative antibiotic in high-risk patients.
What other medicines interact with Gliclazide?
MediHelp also lists interactions of Gliclazide with, for example, Ciprofloxacin, Clarithromycin, Disopyramide. The full list is on the Gliclazide page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
