दवाओं की अंतःक्रिया
Imipramine + Rasagiline
गंभीरता: निषिद्ध
Imipramine and Rasagiline: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Combining a tricyclic antidepressant with an MAO-B inhibitor has been associated with serious reactions including serotonin syndrome, hyperpyrexia and severe CNS toxicity. Labeling advises against concurrent use and separating the drugs by a washout period.
इस इंटरैक्शन का सरल भाषा में अर्थ
Imipramine and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Imipramine belongs to Central Nervous System; Rasagiline belongs to Central Nervous System.
ऐसा क्यों होता है
MAO inhibition combined with tricyclic reuptake blockade increases synaptic monoamines, causing serotonergic and adrenergic toxicity.
क्या करें
Do not co-administer; allow at least 14 days after stopping rasagiline before starting imipramine, and an adequate tricyclic washout before rasagiline.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Imipramine और Rasagiline की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Imipramine के अन्य इंटरैक्शन
- Dronedarone + Imipramine निषिद्ध
- Imipramine + Isocarboxazid निषिद्ध
- Imipramine + Phenelzine निषिद्ध
- Imipramine + Pimozide निषिद्ध
- Imipramine + Safinamide निषिद्ध
- Imipramine + Selegiline निषिद्ध
Rasagiline के अन्य इंटरैक्शन
- Atomoxetine + Rasagiline निषिद्ध
- Brimonidine + Rasagiline निषिद्ध
- Bupropion-naltrexone + Rasagiline निषिद्ध
- Bupropion + Rasagiline निषिद्ध
- Clomipramine + Rasagiline निषिद्ध
- Desvenlafaxine + Rasagiline निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Imipramine with Rasagiline?
MediHelp rates the interaction as contraindicated. Imipramine and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Combining a tricyclic antidepressant with an MAO-B inhibitor has been associated with serious reactions including serotonin syndrome, hyperpyrexia and severe CNS toxicity. Labeling advises against concurrent use and separating the drugs by a washout period.
How serious is the interaction between Imipramine and Rasagiline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; allow at least 14 days after stopping rasagiline before starting imipramine, and an adequate tricyclic washout before rasagiline.
What other medicines interact with Imipramine?
MediHelp also lists interactions of Imipramine with, for example, Dronedarone, Isocarboxazid, Phenelzine. The full list is on the Imipramine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
