दवाओं की अंतःक्रिया
Measles mumps and rubella vaccine + Tisagenlecleucel
गंभीरता: निषिद्ध
Measles mumps and rubella vaccine and Tisagenlecleucel: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Tisagenlecleucel is a CAR-T cell therapy given after lymphodepleting chemotherapy and is associated with B-cell aplasia and prolonged immune suppression. Live vaccines can cause disseminated vaccine-strain infection in this setting.
इस इंटरैक्शन का सरल भाषा में अर्थ
Measles mumps and rubella vaccine and Tisagenlecleucel are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Measles mumps and rubella vaccine belongs to Miscellaneous; Tisagenlecleucel belongs to Oncology.
ऐसा क्यों होता है
Pharmacodynamic: lymphodepleting chemotherapy and CAR-T mediated B-cell depletion impair control of replicating live vaccine viruses.
क्या करें
Do not give live vaccines from at least 6 weeks before lymphodepletion, during treatment, and until immune recovery is confirmed. Give inactivated vaccines according to specialist guidance after immune reconstitution.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Measles mumps and rubella vaccine और Tisagenlecleucel की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Measles mumps and rubella vaccine के अन्य इंटरैक्शन
- Adalimumab + Measles mumps and rubella vaccine निषिद्ध
- Anakinra + Measles mumps and rubella vaccine निषिद्ध
- Antithymocyte globulin equine + Measles mumps and rubella vaccine निषिद्ध
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine निषिद्ध
- Azathioprine + Measles mumps and rubella vaccine निषिद्ध
- Basiliximab + Measles mumps and rubella vaccine निषिद्ध
Tisagenlecleucel के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Measles mumps and rubella vaccine with Tisagenlecleucel?
MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine and Tisagenlecleucel are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Tisagenlecleucel is a CAR-T cell therapy given after lymphodepleting chemotherapy and is associated with B-cell aplasia and prolonged immune suppression. Live vaccines can cause disseminated vaccine-strain infection in this setting.
How serious is the interaction between Measles mumps and rubella vaccine and Tisagenlecleucel?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines from at least 6 weeks before lymphodepletion, during treatment, and until immune recovery is confirmed. Give inactivated vaccines according to specialist guidance after immune reconstitution.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
