दवाओं की अंतःक्रिया
Measles mumps rubella and varicella vaccine live + Melphalan
गंभीरता: निषिद्ध
Measles mumps rubella and varicella vaccine live and Melphalan: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
MMRV vaccine contains live attenuated viruses, which can replicate without control in a patient immunosuppressed by melphalan. This can lead to disseminated vaccine-virus disease, and the vaccine response is also reduced.
इस इंटरैक्शन का सरल भाषा में अर्थ
Measles mumps rubella and varicella vaccine live and Melphalan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
ऐसा क्यों होता है
Chemotherapy-induced immunosuppression allows unchecked replication of live attenuated virus and impairs the vaccine response.
क्या करें
Avoid live vaccines during melphalan therapy and for at least 3 months after it ends, subject to immune recovery. Give live vaccines at least 4 weeks before starting chemotherapy when possible.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Measles mumps rubella and varicella vaccine live और Melphalan की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Melphalan के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Measles mumps rubella and varicella vaccine live with Melphalan?
MediHelp rates the interaction as contraindicated. Measles mumps rubella and varicella vaccine live and Melphalan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MMRV vaccine contains live attenuated viruses, which can replicate without control in a patient immunosuppressed by melphalan. This can lead to disseminated vaccine-virus disease, and the vaccine response is also reduced.
How serious is the interaction between Measles mumps rubella and varicella vaccine live and Melphalan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during melphalan therapy and for at least 3 months after it ends, subject to immune recovery. Give live vaccines at least 4 weeks before starting chemotherapy when possible.
What other medicines interact with Melphalan?
MediHelp also lists interactions of Melphalan with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Melphalan page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
