दवाओं की अंतःक्रिया
Metformin + Vitamin B12
गंभीरता: मध्यम
Metformin and Vitamin B12: moderate interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Long-term metformin therapy is associated with lower serum vitamin B12 levels and occasionally clinical deficiency, including anemia or neuropathy. The risk rises with higher doses, longer duration and other risk factors such as older age or poor intake.
इस इंटरैक्शन का सरल भाषा में अर्थ
Metformin and Vitamin B12 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Metformin belongs to Endocrine; Vitamin B12 belongs to Gastrointestinal Tract.
ऐसा क्यों होता है
Metformin is thought to impair calcium-dependent ileal absorption of the B12-intrinsic factor complex, though the mechanism is not fully established.
क्या करें
Measure vitamin B12 periodically in patients on long-term metformin, especially those with anemia or neuropathy. Replace B12 if deficient; metformin can usually be continued.
फार्मासिस्ट से क्या पूछें
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Metformin और Vitamin B12 की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Vitamin B12 के अन्य इंटरैक्शन
Metformin के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Metformin with Vitamin B12?
MediHelp rates the interaction as moderate. Metformin and Vitamin B12 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Long-term metformin therapy is associated with lower serum vitamin B12 levels and occasionally clinical deficiency, including anemia or neuropathy. The risk rises with higher doses, longer duration and other risk factors such as older age or poor intake.
How serious is the interaction between Metformin and Vitamin B12?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Measure vitamin B12 periodically in patients on long-term metformin, especially those with anemia or neuropathy. Replace B12 if deficient; metformin can usually be continued.
What other medicines interact with Vitamin B12?
MediHelp also lists interactions of Vitamin B12 with, for example, Chloramphenicol, Dichlorphenamide, Neomycin po. The full list is on the Vitamin B12 page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
