दवाओं की अंतःक्रिया
Mycophenolic acid + Rifampicin
गंभीरता: गंभीर
Mycophenolic acid and Rifampicin: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Rifampicin can lower mycophenolic acid exposure, which may reduce immunosuppression and raise the risk of rejection or graft-versus-host disease. The effect has been seen in transplant recipients and may emerge within days of starting rifampicin.
इस इंटरैक्शन का सरल भाषा में अर्थ
Mycophenolic acid and Rifampicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Mycophenolic acid belongs to Miscellaneous; Rifampicin belongs to Anti Bacterial.
ऐसा क्यों होता है
Rifampicin induces UGT enzymes and may alter enterohepatic recirculation of mycophenolic acid glucuronide, lowering its exposure.
क्या करें
Avoid the combination unless clearly needed; if used, monitor for rejection and consider mycophenolic acid exposure monitoring with dose adjustment. Re-evaluate dosing when rifampicin is stopped.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Mycophenolic acid और Rifampicin की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Mycophenolic acid के अन्य इंटरैक्शन
Rifampicin के अन्य इंटरैक्शन
- Cabotegravir + Rifampicin निषिद्ध
- Delamanid + Rifampicin निषिद्ध
- Doravirine + Rifampicin निषिद्ध
- Ensitrelvir + Rifampicin निषिद्ध
- Fostemsavir + Rifampicin निषिद्ध
- Isavuconazole + Rifampicin निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Mycophenolic acid with Rifampicin?
MediHelp rates the interaction as major. Mycophenolic acid and Rifampicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rifampicin can lower mycophenolic acid exposure, which may reduce immunosuppression and raise the risk of rejection or graft-versus-host disease. The effect has been seen in transplant recipients and may emerge within days of starting rifampicin.
How serious is the interaction between Mycophenolic acid and Rifampicin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination unless clearly needed; if used, monitor for rejection and consider mycophenolic acid exposure monitoring with dose adjustment. Re-evaluate dosing when rifampicin is stopped.
What other medicines interact with Mycophenolic acid?
MediHelp also lists interactions of Mycophenolic acid with, for example, Activated charcoal, Azathioprine, Cholestyramine. The full list is on the Mycophenolic acid page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
