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दवाओं की अंतःक्रिया

Oxcarbazepine + Rilpivirine

गंभीरता: निषिद्ध

Oxcarbazepine and Rilpivirine: contraindicated interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Oxcarbazepine can lower rilpivirine plasma concentrations through induction of CYP3A4. Reduced exposure may lead to loss of virologic suppression and development of resistance to rilpivirine and the NNRTI class.

इस इंटरैक्शन का सरल भाषा में अर्थ

Oxcarbazepine and Rilpivirine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Oxcarbazepine belongs to Central Nervous System; Rilpivirine belongs to Anti Virals.

साक्ष्य स्तर: Moderate

ऐसा क्यों होता है

Oxcarbazepine induces CYP3A4, increasing the metabolism of rilpivirine, a CYP3A4 substrate.

क्या करें

Avoid the combination, as rilpivirine labeling contraindicates enzyme-inducing anticonvulsants of this type. Use an alternative antiseizure drug with no inducing effect, or an alternative antiretroviral regimen.

फार्मासिस्ट से क्या पूछें

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Oxcarbazepine और Rilpivirine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Oxcarbazepine with Rilpivirine?

MediHelp rates the interaction as contraindicated. Oxcarbazepine and Rilpivirine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oxcarbazepine can lower rilpivirine plasma concentrations through induction of CYP3A4. Reduced exposure may lead to loss of virologic suppression and development of resistance to rilpivirine and the NNRTI class.

How serious is the interaction between Oxcarbazepine and Rilpivirine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination, as rilpivirine labeling contraindicates enzyme-inducing anticonvulsants of this type. Use an alternative antiseizure drug with no inducing effect, or an alternative antiretroviral regimen.

What other medicines interact with Oxcarbazepine?

MediHelp also lists interactions of Oxcarbazepine with, for example, Cabotegravir, Artemether / lumefantrine, Atazanavir. The full list is on the Oxcarbazepine page.

MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर

MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।

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