दवाओं की अंतःक्रिया
Ozanimod + Rasagiline
गंभीरता: निषिद्ध
Ozanimod and Rasagiline: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Ozanimod is metabolised to active metabolites that inhibit MAO-B, so adding an MAO inhibitor may lead to hypertensive crisis or serotonin toxicity, and labeling contraindicates concurrent use. MAO-B inhibitors may also change exposure to ozanimod active metabolites.
इस इंटरैक्शन का सरल भाषा में अर्थ
Ozanimod and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ozanimod belongs to Central Nervous System; Rasagiline belongs to Central Nervous System.
ऐसा क्यों होता है
MAO-B inhibition by rasagiline may reduce formation of ozanimod active metabolites and the combined MAO inhibition may cause excess monoamines.
क्या करें
Avoid the combination and consider alternative therapy for multiple sclerosis or Parkinson disease. Allow at least 14 days after stopping ozanimod before starting an MAO inhibitor.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Ozanimod और Rasagiline की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Rasagiline के अन्य इंटरैक्शन
- Atomoxetine + Rasagiline निषिद्ध
- Brimonidine + Rasagiline निषिद्ध
- Bupropion-naltrexone + Rasagiline निषिद्ध
- Bupropion + Rasagiline निषिद्ध
- Clomipramine + Rasagiline निषिद्ध
- Desvenlafaxine + Rasagiline निषिद्ध
Ozanimod के अन्य इंटरैक्शन
- Isocarboxazid + Ozanimod निषिद्ध
- Linezolid + Ozanimod निषिद्ध
- Ozanimod + Phenelzine निषिद्ध
- Ozanimod + Procarbazine निषिद्ध
- Ozanimod + Safinamide निषिद्ध
- Ozanimod + Tranylcypromine निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Ozanimod with Rasagiline?
MediHelp rates the interaction as contraindicated. Ozanimod and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ozanimod is metabolised to active metabolites that inhibit MAO-B, so adding an MAO inhibitor may lead to hypertensive crisis or serotonin toxicity, and labeling contraindicates concurrent use. MAO-B inhibitors may also change exposure to ozanimod active metabolites.
How serious is the interaction between Ozanimod and Rasagiline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and consider alternative therapy for multiple sclerosis or Parkinson disease. Allow at least 14 days after stopping ozanimod before starting an MAO inhibitor.
What other medicines interact with Rasagiline?
MediHelp also lists interactions of Rasagiline with, for example, Atomoxetine, Brimonidine, Bupropion-naltrexone. The full list is on the Rasagiline page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
