दवाओं की अंतःक्रिया
Pexidartinib + Sulphasalazine
गंभीरता: गंभीर
Pexidartinib and Sulphasalazine: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Pexidartinib carries a boxed warning for serious and potentially fatal liver injury, and sulfasalazine can also cause hepatotoxicity. Using both increases the chance of liver injury.
इस इंटरैक्शन का सरल भाषा में अर्थ
Pexidartinib and Sulphasalazine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pexidartinib belongs to Oncology; Sulphasalazine belongs to Gastrointestinal Tract.
ऐसा क्यों होता है
Additive hepatotoxicity from two agents that can each cause liver injury.
क्या करें
Avoid the combination if possible. If both are needed, check liver tests at baseline and frequently, and stop treatment if liver injury develops.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Pexidartinib और Sulphasalazine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Sulphasalazine के अन्य इंटरैक्शन
Pexidartinib के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Pexidartinib with Sulphasalazine?
MediHelp rates the interaction as major. Pexidartinib and Sulphasalazine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Pexidartinib carries a boxed warning for serious and potentially fatal liver injury, and sulfasalazine can also cause hepatotoxicity. Using both increases the chance of liver injury.
How serious is the interaction between Pexidartinib and Sulphasalazine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination if possible. If both are needed, check liver tests at baseline and frequently, and stop treatment if liver injury develops.
What other medicines interact with Sulphasalazine?
MediHelp also lists interactions of Sulphasalazine with, for example, Deferiprone, Sepiapterin, Acalabrutinib. The full list is on the Sulphasalazine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
