दवाओं की अंतःक्रिया
Solifenacin + Trihexyphenidyl
गंभीरता: गंभीर
Solifenacin and Trihexyphenidyl: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Both drugs are antimuscarinic, so combined use can produce marked dry mouth, constipation, urinary retention, blurred vision, tachycardia and confusion. Older adults are especially vulnerable to cognitive impairment and delirium.
इस इंटरैक्शन का सरल भाषा में अर्थ
Solifenacin and Trihexyphenidyl can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Solifenacin belongs to Genitourinary; Trihexyphenidyl belongs to Central Nervous System.
ऐसा क्यों होता है
Additive antagonism of muscarinic receptors.
क्या करें
Avoid the combination where possible, particularly in older adults. If necessary, use the lowest effective doses and monitor for urinary retention, constipation and cognitive changes.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Solifenacin और Trihexyphenidyl की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Solifenacin के अन्य इंटरैक्शन
Trihexyphenidyl के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Solifenacin with Trihexyphenidyl?
MediHelp rates the interaction as major. Solifenacin and Trihexyphenidyl can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs are antimuscarinic, so combined use can produce marked dry mouth, constipation, urinary retention, blurred vision, tachycardia and confusion. Older adults are especially vulnerable to cognitive impairment and delirium.
How serious is the interaction between Solifenacin and Trihexyphenidyl?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, particularly in older adults. If necessary, use the lowest effective doses and monitor for urinary retention, constipation and cognitive changes.
What other medicines interact with Solifenacin?
MediHelp also lists interactions of Solifenacin with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Solifenacin page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
