Лекарственные взаимодействия
Anti-thymocyte + Measles vaccine
Тяжесть: Противопоказано
Anti-thymocyte and Measles vaccine: contraindicated interaction.
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Кратко
Measles vaccine is a live attenuated vaccine, and in a patient profoundly immunosuppressed by anti-thymocyte globulin the vaccine virus may replicate unchecked and cause disseminated disease. The vaccine response will also be poor.
Что означает это взаимодействие простыми словами
Anti-thymocyte and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Почему это происходит
Impaired cell-mediated immunity permits uncontrolled replication of live attenuated virus.
Что делать
Do not give live measles vaccine during and for an extended period after anti-thymocyte globulin until immune recovery is confirmed. Give it at least 4 weeks before starting therapy if vaccination is needed.
О чём спросить фармацевта
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Другие взаимодействия Anti-thymocyte
- Anti-thymocyte + Bcg vaccine live Противопоказано
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal Противопоказано
- Anti-thymocyte + Measles mumps and rubella vaccine live Противопоказано
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live Противопоказано
- Anti-thymocyte + Rotavirus oral vaccine live Противопоказано
- Anti-thymocyte + Rubella vaccine Противопоказано
Частые вопросы
Can I take Anti-thymocyte with Measles vaccine?
MediHelp rates the interaction as contraindicated. Anti-thymocyte and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is a live attenuated vaccine, and in a patient profoundly immunosuppressed by anti-thymocyte globulin the vaccine virus may replicate unchecked and cause disseminated disease. The vaccine response will also be poor.
How serious is the interaction between Anti-thymocyte and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live measles vaccine during and for an extended period after anti-thymocyte globulin until immune recovery is confirmed. Give it at least 4 weeks before starting therapy if vaccination is needed.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.
Полные монографии, дозировки и проверка взаимодействий в приложении MediHelp
Откройте полный справочник, проверяйте взаимодействия нескольких препаратов и пользуйтесь инструментами дозирования в приложении MediHelp.
