Лекарственные взаимодействия
Azathioprine + Measles mumps and rubella vaccine
Тяжесть: Противопоказано
Azathioprine and Measles mumps and rubella vaccine: contraindicated interaction.
Последнее обновление
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Кратко
The live attenuated vaccine relies on a competent immune system to limit viral replication, and azathioprine (a purine-antimetabolite immunosuppressant) weakens that control. Disseminated vaccine-strain infection is possible and the antibody response to the vaccine may also be reduced.
Что означает это взаимодействие простыми словами
Azathioprine and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Azathioprine belongs to Gastrointestinal Tract; Measles mumps and rubella vaccine belongs to Miscellaneous.
Почему это происходит
Azathioprine-mediated immunosuppression allows replication of a live attenuated virus
Что делать
Do not give live vaccines during treatment; where possible, vaccinate at least 4 weeks before starting the immunosuppressant, and delay after stopping until immune function has recovered.
О чём спросить фармацевта
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Другие взаимодействия Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Противопоказано
- Anakinra + Measles mumps and rubella vaccine Противопоказано
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Противопоказано
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Противопоказано
- Basiliximab + Measles mumps and rubella vaccine Противопоказано
- Certolizumab pegol + Measles mumps and rubella vaccine Противопоказано
Другие взаимодействия Azathioprine
- Adenovirus types 4 and 7 live + Azathioprine Противопоказано
- Azathioprine + Bcg vaccine live Противопоказано
- Azathioprine + Febuxostat Противопоказано
- Azathioprine + Influenza virus vaccine quadrivalent intranasal Противопоказано
- Azathioprine + Measles mumps and rubella vaccine live Противопоказано
- Azathioprine + Measles mumps rubella and varicella vaccine live Противопоказано
Частые вопросы
Can I take Azathioprine with Measles mumps and rubella vaccine?
MediHelp rates the interaction as contraindicated. Azathioprine and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The live attenuated vaccine relies on a competent immune system to limit viral replication, and azathioprine (a purine-antimetabolite immunosuppressant) weakens that control. Disseminated vaccine-strain infection is possible and the antibody response to the vaccine may also be reduced.
How serious is the interaction between Azathioprine and Measles mumps and rubella vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during treatment; where possible, vaccinate at least 4 weeks before starting the immunosuppressant, and delay after stopping until immune function has recovered.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
Полные монографии, дозировки и проверка взаимодействий в приложении MediHelp
Откройте полный справочник, проверяйте взаимодействия нескольких препаратов и пользуйтесь инструментами дозирования в приложении MediHelp.
