Лекарственные взаимодействия
Bacitracin-neomycin-polymyxin + Cidofovir
Тяжесть: Тяжёлое
Bacitracin-neomycin-polymyxin and Cidofovir: major interaction.
Последнее обновление
Для специалистов здравоохранения — только для справки. Эта страница — краткая сводка, а не медицинская консультация и не замена официальной инструкции или клинического суждения. Всегда проверяйте перед назначением или отпуском.
Клиническое содержание этой страницы доступно только на английском языке.
Кратко
Systemic polymyxin B, neomycin and bacitracin are nephrotoxic, and cidofovir causes dose-limiting proximal tubular kidney injury. Combined exposure may cause severe renal damage, and cidofovir labeling contraindicates concurrent nephrotoxic agents. Risk applies mainly to systemic or heavily absorbed use rather than small topical applications.
Что означает это взаимодействие простыми словами
Bacitracin-neomycin-polymyxin and Cidofovir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bacitracin-neomycin-polymyxin belongs to Anti Bacterial; Cidofovir belongs to Anti Virals.
Почему это происходит
Additive nephrotoxicity through direct renal tubular injury by both agents.
Что делать
Avoid systemic or heavily absorbed use of these antibiotics during and shortly after cidofovir therapy. If unavoidable, monitor serum creatinine and urine protein closely.
О чём спросить фармацевта
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Для подписчиков Pro+
Откройте страницу целиком
Создайте аккаунт и начните пробный период Pro+, чтобы открыть полные рекомендации по ведению для Bacitracin-neomycin-polymyxin и Cidofovir, дополнительные примечания, подробности о доказательной базе и проверку взаимодействий для всего рецепта.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ бесплатно 14 дней на сайте. Карта не нужна.
Другие взаимодействия Bacitracin-neomycin-polymyxin
- Allogeneic cultured keratinocytes / fibroblasts in bovine collagen + Bacitracin-neomycin-polymyxin Тяжёлое
- Atracurium + Bacitracin-neomycin-polymyxin Тяжёлое
- Bacitracin-neomycin-polymyxin + Capreomycin Тяжёлое
- Bacitracin-neomycin-polymyxin + Cisatracurium Тяжёлое
- Bacitracin-neomycin-polymyxin + Pancuronium Тяжёлое
- Bacitracin-neomycin-polymyxin + Rocuronium Тяжёлое
Другие взаимодействия Cidofovir
- Amikacin + Cidofovir Противопоказано
- Amphotericin b deoxycholate + Cidofovir Противопоказано
- Amphotericin b + Cidofovir Противопоказано
- Bacitracin + Cidofovir Противопоказано
- Capreomycin + Cidofovir Противопоказано
- Cephaloridine + Cidofovir Противопоказано
Частые вопросы
Can I take Bacitracin-neomycin-polymyxin with Cidofovir?
MediHelp rates the interaction as major. Bacitracin-neomycin-polymyxin and Cidofovir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Systemic polymyxin B, neomycin and bacitracin are nephrotoxic, and cidofovir causes dose-limiting proximal tubular kidney injury. Combined exposure may cause severe renal damage, and cidofovir labeling contraindicates concurrent nephrotoxic agents. Risk applies mainly to systemic or heavily absorbed use rather than small topical applications.
How serious is the interaction between Bacitracin-neomycin-polymyxin and Cidofovir?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic or heavily absorbed use of these antibiotics during and shortly after cidofovir therapy. If unavoidable, monitor serum creatinine and urine protein closely.
What other medicines interact with Bacitracin-neomycin-polymyxin?
MediHelp also lists interactions of Bacitracin-neomycin-polymyxin with, for example, Allogeneic cultured keratinocytes / fibroblasts in bovine collagen, Atracurium, Capreomycin. The full list is on the Bacitracin-neomycin-polymyxin page.
Полные монографии, дозировки и проверка взаимодействий в приложении MediHelp
Откройте полный справочник, проверяйте взаимодействия нескольких препаратов и пользуйтесь инструментами дозирования в приложении MediHelp.
