Лекарственные взаимодействия
Balsalazide + Varicella virus vaccine live
Тяжесть: Тяжёлое
Balsalazide and Varicella virus vaccine live: major interaction.
Последнее обновление
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Кратко
Balsalazide is converted to mesalamine, a salicylate, and salicylate use after live varicella vaccination has been linked to Reye's syndrome in children. The risk is largely theoretical given balsalazide's low systemic salicylate exposure, but it is a labeled caution.
Что означает это взаимодействие простыми словами
Balsalazide and Varicella virus vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Почему это происходит
Salicylate exposure after live varicella virus vaccination is thought to predispose to Reye's syndrome; the precise mechanism is not established.
Что делать
Avoid salicylate-containing products, including balsalazide, for about 6 weeks after vaccination in children and adolescents where possible. If balsalazide is essential, weigh the risks and benefits and counsel caregivers to report vomiting or altered behavior.
О чём спросить фармацевта
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Другие взаимодействия Balsalazide
- Balsalazide + Measles mumps rubella and varicella vaccine live Тяжёлое
- Aceclofenac + Balsalazide Умеренное
- Balsalazide + Celecoxib Умеренное
- Balsalazide + Mesalamine Умеренное
- Balsalazide + Vadadustat Умеренное
- Balsalazide + Voclosporin Умеренное
Частые вопросы
Can I take Balsalazide with Varicella virus vaccine live?
MediHelp rates the interaction as major. Balsalazide and Varicella virus vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Balsalazide is converted to mesalamine, a salicylate, and salicylate use after live varicella vaccination has been linked to Reye's syndrome in children. The risk is largely theoretical given balsalazide's low systemic salicylate exposure, but it is a labeled caution.
How serious is the interaction between Balsalazide and Varicella virus vaccine live?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid salicylate-containing products, including balsalazide, for about 6 weeks after vaccination in children and adolescents where possible. If balsalazide is essential, weigh the risks and benefits and counsel caregivers to report vomiting or altered behavior.
What other medicines interact with Balsalazide?
MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Aceclofenac, Celecoxib. The full list is on the Balsalazide page.
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