Лекарственные взаимодействия
Mesalamine + Varicella virus vaccine live
Тяжесть: Тяжёлое
Mesalamine and Varicella virus vaccine live: major interaction.
Последнее обновление
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Кратко
Mesalamine is a 5-aminosalicylate, and salicylate use after live varicella vaccination has been linked to Reye's syndrome in children. Systemic salicylate exposure from mesalamine is low, so the risk is theoretical but is included in labeling.
Что означает это взаимодействие простыми словами
Mesalamine and Varicella virus vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Почему это происходит
Salicylate exposure after live varicella virus vaccination is thought to predispose to Reye's syndrome; the precise mechanism is not established.
Что делать
Avoid salicylate-containing products, including mesalamine, for about 6 weeks after vaccination in children and adolescents where possible. If mesalamine is essential, weigh the risks and benefits and counsel caregivers to report vomiting or altered behavior.
О чём спросить фармацевта
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Другие взаимодействия Mesalamine
- Measles mumps rubella and varicella vaccine live + Mesalamine Тяжёлое
- Aceclofenac + Mesalamine Умеренное
- Acemetacin + Mesalamine Умеренное
- Acetylsalicylic acid + Mesalamine Умеренное
- Aspirin / citric acid / sodium bicarbonate + Mesalamine Умеренное
- Aspirin rectal + Mesalamine Умеренное
Частые вопросы
Can I take Mesalamine with Varicella virus vaccine live?
MediHelp rates the interaction as major. Mesalamine and Varicella virus vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Mesalamine is a 5-aminosalicylate, and salicylate use after live varicella vaccination has been linked to Reye's syndrome in children. Systemic salicylate exposure from mesalamine is low, so the risk is theoretical but is included in labeling.
How serious is the interaction between Mesalamine and Varicella virus vaccine live?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid salicylate-containing products, including mesalamine, for about 6 weeks after vaccination in children and adolescents where possible. If mesalamine is essential, weigh the risks and benefits and counsel caregivers to report vomiting or altered behavior.
What other medicines interact with Mesalamine?
MediHelp also lists interactions of Mesalamine with, for example, Measles mumps rubella and varicella vaccine live, Aceclofenac, Acemetacin. The full list is on the Mesalamine page.
Полные монографии, дозировки и проверка взаимодействий в приложении MediHelp
Откройте полный справочник, проверяйте взаимодействия нескольких препаратов и пользуйтесь инструментами дозирования в приложении MediHelp.
