دوا کے تعاملات
Amitriptyline + Methylene blue
شدت: مانع استعمال
Amitriptyline and Methylene blue: contraindicated interaction.
آخری تازہ کاری
صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔
اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔
خلاصہ
Methylene blue inhibits MAO-A and, with a serotonergic tricyclic such as amitriptyline, can precipitate serotonin syndrome. This has been reported with other serotonergic antidepressants and the risk is labelled.
اس تعامل کا آسان لفظوں میں مطلب
Amitriptyline and Methylene blue are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
ایسا کیوں ہوتا ہے
MAO-A inhibition by methylene blue combined with serotonin reuptake inhibition by amitriptyline.
کیا کرنا ہے
Avoid the combination in non-emergency settings. If urgent methylene blue treatment is essential, stop amitriptyline and monitor for serotonin toxicity for up to 2 weeks or until 24 hours after the last methylene blue dose, whichever comes first.
فارماسسٹ سے کیا پوچھیں
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ اراکین کے لیے
پورا صفحہ کھولیں
Amitriptyline اور Methylene blue کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
ویب پر 14 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔
Amitriptyline کے دیگر تعاملات
- Amitriptyline + Isocarboxazid مانع استعمال
- Amitriptyline + Phenelzine مانع استعمال
- Amitriptyline + Pimozide مانع استعمال
- Amitriptyline + Procarbazine مانع استعمال
- Amitriptyline + Safinamide مانع استعمال
- Amitriptyline + Selegiline مانع استعمال
اکثر پوچھے جانے والے سوالات
Can I take Amitriptyline with Methylene blue?
MediHelp rates the interaction as contraindicated. Amitriptyline and Methylene blue are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methylene blue inhibits MAO-A and, with a serotonergic tricyclic such as amitriptyline, can precipitate serotonin syndrome. This has been reported with other serotonergic antidepressants and the risk is labelled.
How serious is the interaction between Amitriptyline and Methylene blue?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in non-emergency settings. If urgent methylene blue treatment is essential, stop amitriptyline and monitor for serotonin toxicity for up to 2 weeks or until 24 hours after the last methylene blue dose, whichever comes first.
What other medicines interact with Amitriptyline?
MediHelp also lists interactions of Amitriptyline with, for example, Isocarboxazid, Phenelzine, Pimozide. The full list is on the Amitriptyline page.
MediHelp ایپ میں مکمل مونوگراف، خوراک اور تعامل چیکر
MediHelp ایپ میں مکمل حوالہ کھولیں، متعدد ادویات کے تعاملات جانچیں اور خوراک کے ٹولز استعمال کریں۔
