دوا کے تعاملات
Buprenorphine long-acting + Phenelzine
شدت: مانع استعمال
Buprenorphine long-acting and Phenelzine: contraindicated interaction.
آخری تازہ کاری
صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔
اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔
خلاصہ
Combining an MAO inhibitor with buprenorphine may cause serotonin syndrome or opioid toxicity, including respiratory depression and coma. Long-acting injectable buprenorphine cannot be quickly withdrawn, which prolongs exposure if a reaction occurs. Labeling advises against use during or within 14 days of MAOI therapy.
اس تعامل کا آسان لفظوں میں مطلب
Buprenorphine long-acting and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
ایسا کیوں ہوتا ہے
Additive serotonergic effects and potentiation of opioid CNS and respiratory depression, possibly through altered opioid metabolism, in the setting of MAO inhibition.
کیا کرنا ہے
Do not start long-acting buprenorphine within 14 days of stopping phenelzine or while it is being taken. Choose a non-serotonergic alternative or allow an adequate washout.
فارماسسٹ سے کیا پوچھیں
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ اراکین کے لیے
پورا صفحہ کھولیں
Buprenorphine long-acting اور Phenelzine کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
ویب پر 14 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔
Phenelzine کے دیگر تعاملات
- 5-HTP + Phenelzine مانع استعمال
- Amitriptyline + Phenelzine مانع استعمال
- Amoxapine + Phenelzine مانع استعمال
- Atomoxetine + Phenelzine مانع استعمال
- Benzphetamine + Phenelzine مانع استعمال
- Brimonidine + Phenelzine مانع استعمال
اکثر پوچھے جانے والے سوالات
Can I take Buprenorphine long-acting with Phenelzine?
MediHelp rates the interaction as contraindicated. Buprenorphine long-acting and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Combining an MAO inhibitor with buprenorphine may cause serotonin syndrome or opioid toxicity, including respiratory depression and coma. Long-acting injectable buprenorphine cannot be quickly withdrawn, which prolongs exposure if a reaction occurs. Labeling advises against use during or within 14 days of MAOI therapy.
How serious is the interaction between Buprenorphine long-acting and Phenelzine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not start long-acting buprenorphine within 14 days of stopping phenelzine or while it is being taken. Choose a non-serotonergic alternative or allow an adequate washout.
What other medicines interact with Phenelzine?
MediHelp also lists interactions of Phenelzine with, for example, 5-HTP, Amitriptyline, Amoxapine. The full list is on the Phenelzine page.
MediHelp ایپ میں مکمل مونوگراف، خوراک اور تعامل چیکر
MediHelp ایپ میں مکمل حوالہ کھولیں، متعدد ادویات کے تعاملات جانچیں اور خوراک کے ٹولز استعمال کریں۔
