دوا کے تعاملات
Cilastatin-imipenem + Sodium picosulfate
شدت: معتدل
Cilastatin-imipenem and Sodium picosulfate: moderate interaction.
آخری تازہ کاری
صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔
اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔
خلاصہ
Sodium picosulfate is a prodrug that needs colonic bacteria to be converted to its active laxative form. Systemic antibiotics such as imipenem may disturb the colonic flora and reduce this activation, which can lead to a poorer bowel cleansing result before colonoscopy.
اس تعامل کا آسان لفظوں میں مطلب
Cilastatin-imipenem and Sodium picosulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
ایسا کیوں ہوتا ہے
Antibiotic-induced suppression of colonic bacteria reduces conversion of picosulfate to its active metabolite.
کیا کرنا ہے
Where possible, avoid scheduling bowel preparation during an antibiotic course, or confirm the quality of bowel cleansing before the procedure. Consider an alternative preparation not dependent on bacterial activation if cleansing is likely to be inadequate.
فارماسسٹ سے کیا پوچھیں
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ اراکین کے لیے
پورا صفحہ کھولیں
Cilastatin-imipenem اور Sodium picosulfate کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
ویب پر 14 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔
Cilastatin-imipenem کے دیگر تعاملات
اکثر پوچھے جانے والے سوالات
Can I take Cilastatin-imipenem with Sodium picosulfate?
MediHelp rates the interaction as moderate. Cilastatin-imipenem and Sodium picosulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium picosulfate is a prodrug that needs colonic bacteria to be converted to its active laxative form. Systemic antibiotics such as imipenem may disturb the colonic flora and reduce this activation, which can lead to a poorer bowel cleansing result before colonoscopy.
How serious is the interaction between Cilastatin-imipenem and Sodium picosulfate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where possible, avoid scheduling bowel preparation during an antibiotic course, or confirm the quality of bowel cleansing before the procedure. Consider an alternative preparation not dependent on bacterial activation if cleansing is likely to be inadequate.
What other medicines interact with Cilastatin-imipenem?
MediHelp also lists interactions of Cilastatin-imipenem with, for example, Divalproex, Ganciclovir, Valproic acid. The full list is on the Cilastatin-imipenem page.
MediHelp ایپ میں مکمل مونوگراف، خوراک اور تعامل چیکر
MediHelp ایپ میں مکمل حوالہ کھولیں، متعدد ادویات کے تعاملات جانچیں اور خوراک کے ٹولز استعمال کریں۔
