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Citalopram + Isocarboxazid

شدت: مانع استعمال

Citalopram and Isocarboxazid: contraindicated interaction.

آخری تازہ کاری

صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔

اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔

خلاصہ

Citalopram raises synaptic serotonin by blocking reuptake, and isocarboxazid (an irreversible non-selective MAO inhibitor) prevents its breakdown. Serotonin syndrome with agitation, hyperthermia, clonus and autonomic instability can develop, sometimes fatally.

اس تعامل کا آسان لفظوں میں مطلب

Citalopram and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Citalopram belongs to Central Nervous System; Isocarboxazid belongs to Central Nervous System.

شواہد کی سطح: High

ایسا کیوں ہوتا ہے

Serotonin reuptake inhibition combined with MAO inhibition causes excess serotonergic activity

کیا کرنا ہے

Contraindicated. Wait at least 14 days after stopping isocarboxazid before starting the other drug; allow at least 2 weeks between stopping an irreversible MAOI and starting citalopram, and about a week the other way round.

فارماسسٹ سے کیا پوچھیں

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ اراکین کے لیے

پورا صفحہ کھولیں

Citalopram اور Isocarboxazid کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

ویب پر 14 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔

اکثر پوچھے جانے والے سوالات

Can I take Citalopram with Isocarboxazid?

MediHelp rates the interaction as contraindicated. Citalopram and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Citalopram raises synaptic serotonin by blocking reuptake, and isocarboxazid (an irreversible non-selective MAO inhibitor) prevents its breakdown. Serotonin syndrome with agitation, hyperthermia, clonus and autonomic instability can develop, sometimes fatally.

How serious is the interaction between Citalopram and Isocarboxazid?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Contraindicated. Wait at least 14 days after stopping isocarboxazid before starting the other drug; allow at least 2 weeks between stopping an irreversible MAOI and starting citalopram, and about a week the other way round.

What other medicines interact with Citalopram?

MediHelp also lists interactions of Citalopram with, for example, Cisapride, Dronedarone, Escitalopram. The full list is on the Citalopram page.

MediHelp ایپ میں مکمل مونوگراف، خوراک اور تعامل چیکر

MediHelp ایپ میں مکمل حوالہ کھولیں، متعدد ادویات کے تعاملات جانچیں اور خوراک کے ٹولز استعمال کریں۔

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