دوا کے تعاملات
Cyclobenzaprine + Tranylcypromine
شدت: مانع استعمال
Cyclobenzaprine and Tranylcypromine: contraindicated interaction.
آخری تازہ کاری
صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔
اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔
خلاصہ
Tranylcypromine inhibits monoamine oxidase and so reduces serotonin breakdown, while cyclobenzaprine is a tricyclic-related muscle relaxant that inhibits serotonin and norepinephrine reuptake. Together this can precipitate serotonin syndrome, with agitation, hyperthermia, clonus and autonomic instability that may be fatal. Hypertensive reactions are also possible with tricyclic agents.
اس تعامل کا آسان لفظوں میں مطلب
Cyclobenzaprine and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Cyclobenzaprine belongs to Musculoskeletal; Tranylcypromine belongs to Central Nervous System.
ایسا کیوں ہوتا ہے
Additive serotonergic activity: irreversible non-selective MAO inhibition plus monoamine reuptake inhibition
کیا کرنا ہے
Do not combine; allow at least 14 days after stopping the tranylcypromine before starting cyclobenzaprine, and at least 14 days after stopping cyclobenzaprine before starting the tranylcypromine.
فارماسسٹ سے کیا پوچھیں
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ اراکین کے لیے
پورا صفحہ کھولیں
Cyclobenzaprine اور Tranylcypromine کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
ویب پر 14 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔
Cyclobenzaprine کے دیگر تعاملات
- Cyclobenzaprine + Isocarboxazid مانع استعمال
- Cyclobenzaprine + Linezolid مانع استعمال
- Cyclobenzaprine + Phenelzine مانع استعمال
- Cyclobenzaprine + Safinamide مانع استعمال
- Cyclobenzaprine + Selegiline مانع استعمال
- Cyclobenzaprine + Selegiline transdermal مانع استعمال
Tranylcypromine کے دیگر تعاملات
- 5-HTP + Tranylcypromine مانع استعمال
- Amitriptyline + Tranylcypromine مانع استعمال
- Amoxapine + Tranylcypromine مانع استعمال
- Atomoxetine + Tranylcypromine مانع استعمال
- Benzphetamine + Tranylcypromine مانع استعمال
- Brimonidine + Tranylcypromine مانع استعمال
اکثر پوچھے جانے والے سوالات
Can I take Cyclobenzaprine with Tranylcypromine?
MediHelp rates the interaction as contraindicated. Cyclobenzaprine and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Tranylcypromine inhibits monoamine oxidase and so reduces serotonin breakdown, while cyclobenzaprine is a tricyclic-related muscle relaxant that inhibits serotonin and norepinephrine reuptake. Together this can precipitate serotonin syndrome, with agitation, hyperthermia, clonus and autonomic instability that may be fatal. Hypertensive reactions are also possible with tricyclic agents.
How serious is the interaction between Cyclobenzaprine and Tranylcypromine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; allow at least 14 days after stopping the tranylcypromine before starting cyclobenzaprine, and at least 14 days after stopping cyclobenzaprine before starting the tranylcypromine.
What other medicines interact with Cyclobenzaprine?
MediHelp also lists interactions of Cyclobenzaprine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Cyclobenzaprine page.
MediHelp ایپ میں مکمل مونوگراف، خوراک اور تعامل چیکر
MediHelp ایپ میں مکمل حوالہ کھولیں، متعدد ادویات کے تعاملات جانچیں اور خوراک کے ٹولز استعمال کریں۔
