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Cyclosporin + Rifaximin

شدت: معتدل

Cyclosporin and Rifaximin: moderate interaction.

آخری تازہ کاری

صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔

اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔

خلاصہ

Cyclosporine markedly increases systemic absorption of rifaximin, which is normally minimally absorbed. In patients with intact gut barrier this has been very large, and the consequences of such exposure are not well defined.

اس تعامل کا آسان لفظوں میں مطلب

Cyclosporin and Rifaximin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cyclosporin belongs to Miscellaneous; Rifaximin belongs to Anti Bacterial.

شواہد کی سطح: Moderate

ایسا کیوں ہوتا ہے

Cyclosporine inhibits P-glycoprotein, which limits rifaximin absorption, greatly increasing systemic rifaximin levels.

کیا کرنا ہے

Avoid combining where possible, particularly in patients with severe hepatic impairment. If used, monitor for adverse effects of rifaximin and for changes in cyclosporine levels.

فارماسسٹ سے کیا پوچھیں

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ اراکین کے لیے

پورا صفحہ کھولیں

Cyclosporin اور Rifaximin کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

ویب پر 7 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔

اکثر پوچھے جانے والے سوالات

Can I take Cyclosporin with Rifaximin?

MediHelp rates the interaction as moderate. Cyclosporin and Rifaximin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cyclosporine markedly increases systemic absorption of rifaximin, which is normally minimally absorbed. In patients with intact gut barrier this has been very large, and the consequences of such exposure are not well defined.

How serious is the interaction between Cyclosporin and Rifaximin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where possible, particularly in patients with severe hepatic impairment. If used, monitor for adverse effects of rifaximin and for changes in cyclosporine levels.

What other medicines interact with Cyclosporin?

MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.

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