دوا کے تعاملات
Dicloxacillin + Phenindione
شدت: شدید
Dicloxacillin and Phenindione: major interaction.
آخری تازہ کاری
صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔
اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔
خلاصہ
Dicloxacillin has been reported to reduce the anticoagulant effect of vitamin K antagonists such as warfarin, and a similar effect is expected with phenindione. Loss of anticoagulation raises the risk of thromboembolism, and the INR may fall during treatment and rise again after the antibiotic is stopped.
اس تعامل کا آسان لفظوں میں مطلب
Dicloxacillin and Phenindione can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ایسا کیوں ہوتا ہے
Probable induction of hepatic enzymes by dicloxacillin increasing metabolism of the anticoagulant.
کیا کرنا ہے
Check INR within a few days of starting dicloxacillin and adjust the phenindione dose; recheck after stopping the antibiotic as the dose may need to be reduced again.
فارماسسٹ سے کیا پوچھیں
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ اراکین کے لیے
پورا صفحہ کھولیں
Dicloxacillin اور Phenindione کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
ویب پر 14 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔
Dicloxacillin کے دیگر تعاملات
اکثر پوچھے جانے والے سوالات
Can I take Dicloxacillin with Phenindione?
MediHelp rates the interaction as major. Dicloxacillin and Phenindione can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dicloxacillin has been reported to reduce the anticoagulant effect of vitamin K antagonists such as warfarin, and a similar effect is expected with phenindione. Loss of anticoagulation raises the risk of thromboembolism, and the INR may fall during treatment and rise again after the antibiotic is stopped.
How serious is the interaction between Dicloxacillin and Phenindione?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check INR within a few days of starting dicloxacillin and adjust the phenindione dose; recheck after stopping the antibiotic as the dose may need to be reduced again.
What other medicines interact with Dicloxacillin?
MediHelp also lists interactions of Dicloxacillin with, for example, Atogepant, Axitinib, Bcg vaccine live. The full list is on the Dicloxacillin page.
MediHelp ایپ میں مکمل مونوگراف، خوراک اور تعامل چیکر
MediHelp ایپ میں مکمل حوالہ کھولیں، متعدد ادویات کے تعاملات جانچیں اور خوراک کے ٹولز استعمال کریں۔
