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Hydromorphone + Tranylcypromine

شدت: مانع استعمال

Hydromorphone and Tranylcypromine: contraindicated interaction.

آخری تازہ کاری

صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔

اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔

خلاصہ

Opioids given with nonselective MAOIs have caused severe reactions including hypotension, hyperthermia, respiratory depression and coma. Hydromorphone labeling advises against use during or within 14 days of MAOI therapy.

اس تعامل کا آسان لفظوں میں مطلب

Hydromorphone and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Hydromorphone belongs to Musculoskeletal; Tranylcypromine belongs to Central Nervous System.

شواہد کی سطح: Moderate

ایسا کیوں ہوتا ہے

Irreversible MAO inhibition may potentiate opioid CNS and respiratory depression and cause serotonergic or autonomic instability; the exact mechanism is not fully defined.

کیا کرنا ہے

Do not combine and wait at least 14 days after stopping tranylcypromine before starting hydromorphone. Use an alternative analgesic if an MAOI is required.

فارماسسٹ سے کیا پوچھیں

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ اراکین کے لیے

پورا صفحہ کھولیں

Hydromorphone اور Tranylcypromine کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

ویب پر 14 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔

اکثر پوچھے جانے والے سوالات

Can I take Hydromorphone with Tranylcypromine?

MediHelp rates the interaction as contraindicated. Hydromorphone and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Opioids given with nonselective MAOIs have caused severe reactions including hypotension, hyperthermia, respiratory depression and coma. Hydromorphone labeling advises against use during or within 14 days of MAOI therapy.

How serious is the interaction between Hydromorphone and Tranylcypromine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine and wait at least 14 days after stopping tranylcypromine before starting hydromorphone. Use an alternative analgesic if an MAOI is required.

What other medicines interact with Hydromorphone?

MediHelp also lists interactions of Hydromorphone with, for example, Alvimopan, Bupropion-naltrexone, Isocarboxazid. The full list is on the Hydromorphone page.

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