دوا کے تعاملات
Influenza virus vaccine quadrivalent intranasal + Siponimod
شدت: مانع استعمال
Influenza virus vaccine quadrivalent intranasal and Siponimod: contraindicated interaction.
آخری تازہ کاری
صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔
اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔
خلاصہ
The intranasal influenza vaccine contains live attenuated virus, which could cause vaccine-strain infection in a patient with siponimod-induced lymphopenia. Immune suppression also makes the vaccine response unreliable. Live vaccines should not be given during siponimod therapy.
اس تعامل کا آسان لفظوں میں مطلب
Influenza virus vaccine quadrivalent intranasal and Siponimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
ایسا کیوں ہوتا ہے
Lymphocyte sequestration by S1P receptor modulation impairs control of live attenuated virus replication.
کیا کرنا ہے
Avoid live attenuated vaccines during siponimod and for about 4 weeks after discontinuation; use an inactivated influenza vaccine instead. If a live vaccine is needed, give it at least 4 weeks before starting siponimod.
فارماسسٹ سے کیا پوچھیں
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ اراکین کے لیے
پورا صفحہ کھولیں
Influenza virus vaccine quadrivalent intranasal اور Siponimod کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
ویب پر 14 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔
Siponimod کے دیگر تعاملات
- Cladribine + Siponimod مانع استعمال
- Fingolimod + Siponimod مانع استعمال
- Fluconazole + Siponimod مانع استعمال
- Ponesimod + Siponimod مانع استعمال
- Siponimod + Thioridazine مانع استعمال
- Adenovirus types 4 and 7 live + Siponimod شدید
اکثر پوچھے جانے والے سوالات
Can I take Influenza virus vaccine quadrivalent intranasal with Siponimod?
MediHelp rates the interaction as contraindicated. Influenza virus vaccine quadrivalent intranasal and Siponimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which could cause vaccine-strain infection in a patient with siponimod-induced lymphopenia. Immune suppression also makes the vaccine response unreliable. Live vaccines should not be given during siponimod therapy.
How serious is the interaction between Influenza virus vaccine quadrivalent intranasal and Siponimod?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live attenuated vaccines during siponimod and for about 4 weeks after discontinuation; use an inactivated influenza vaccine instead. If a live vaccine is needed, give it at least 4 weeks before starting siponimod.
What other medicines interact with Siponimod?
MediHelp also lists interactions of Siponimod with, for example, Cladribine, Fingolimod, Fluconazole. The full list is on the Siponimod page.
MediHelp ایپ میں مکمل مونوگراف، خوراک اور تعامل چیکر
MediHelp ایپ میں مکمل حوالہ کھولیں، متعدد ادویات کے تعاملات جانچیں اور خوراک کے ٹولز استعمال کریں۔