دوا کے تعاملات
Methyldopa + Tranylcypromine
شدت: مانع استعمال
Methyldopa and Tranylcypromine: contraindicated interaction.
آخری تازہ کاری ماخذ: US FDA label
صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔
اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔
خلاصہ
MAO inhibitors are listed as contraindicated with methyldopa in labeling because of the risk of hypertensive reactions and excitation, and tranylcypromine may also oppose the hypotensive effect. Methyldopa is metabolised to catecholamine-like compounds that can be potentiated when MAO is inhibited.
اس تعامل کا آسان لفظوں میں مطلب
Methyldopa and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Methyldopa belongs to Cardiovascular; Tranylcypromine belongs to Central Nervous System.
ایسا کیوں ہوتا ہے
MAO inhibition prevents breakdown of methyldopa-derived catecholamine metabolites, causing excess adrenergic stimulation.
کیا کرنا ہے
Do not combine. Allow an adequate washout, about 14 days after stopping the MAOI, before starting methyldopa, and choose another antihypertensive.
فارماسسٹ سے کیا پوچھیں
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ اراکین کے لیے
پورا صفحہ کھولیں
Methyldopa اور Tranylcypromine کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
ویب پر 7 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔
حوالہ جات
Methyldopa کے دیگر تعاملات
Tranylcypromine کے دیگر تعاملات
- 5-HTP + Tranylcypromine مانع استعمال
- Amitriptyline + Tranylcypromine مانع استعمال
- Amoxapine + Tranylcypromine مانع استعمال
- Atomoxetine + Tranylcypromine مانع استعمال
- Benzphetamine + Tranylcypromine مانع استعمال
- Brimonidine + Tranylcypromine مانع استعمال
اکثر پوچھے جانے والے سوالات
Can I take Methyldopa with Tranylcypromine?
MediHelp rates the interaction as contraindicated. Methyldopa and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MAO inhibitors are listed as contraindicated with methyldopa in labeling because of the risk of hypertensive reactions and excitation, and tranylcypromine may also oppose the hypotensive effect. Methyldopa is metabolised to catecholamine-like compounds that can be potentiated when MAO is inhibited.
How serious is the interaction between Methyldopa and Tranylcypromine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine. Allow an adequate washout, about 14 days after stopping the MAOI, before starting methyldopa, and choose another antihypertensive.
What other medicines interact with Methyldopa?
MediHelp also lists interactions of Methyldopa with, for example, Iobenguane i, Lofexidine, Pexidartinib. The full list is on the Methyldopa page.
MediHelp ایپ میں مکمل مونوگراف، خوراک اور تعامل چیکر
MediHelp ایپ میں مکمل حوالہ کھولیں، متعدد ادویات کے تعاملات جانچیں اور خوراک کے ٹولز استعمال کریں۔
