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Ozanimod + Rasagiline

شدت: مانع استعمال

Ozanimod and Rasagiline: contraindicated interaction.

آخری تازہ کاری

صرف صحت کے پیشہ ور افراد کے لیے — محض حوالے کے طور پر۔ یہ صفحہ مختصر خلاصہ ہے، طبی مشورہ نہیں، اور سرکاری لیبل یا طبی فیصلے کا متبادل نہیں۔ تجویز یا فراہمی سے پہلے ہمیشہ تصدیق کریں۔

اس صفحے کا طبی مواد صرف انگریزی میں دستیاب ہے۔

خلاصہ

Ozanimod is metabolised to active metabolites that inhibit MAO-B, so adding an MAO inhibitor may lead to hypertensive crisis or serotonin toxicity, and labeling contraindicates concurrent use. MAO-B inhibitors may also change exposure to ozanimod active metabolites.

اس تعامل کا آسان لفظوں میں مطلب

Ozanimod and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Ozanimod belongs to Central Nervous System; Rasagiline belongs to Central Nervous System.

شواہد کی سطح: Moderate

ایسا کیوں ہوتا ہے

MAO-B inhibition by rasagiline may reduce formation of ozanimod active metabolites and the combined MAO inhibition may cause excess monoamines.

کیا کرنا ہے

Avoid the combination and consider alternative therapy for multiple sclerosis or Parkinson disease. Allow at least 14 days after stopping ozanimod before starting an MAO inhibitor.

فارماسسٹ سے کیا پوچھیں

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ اراکین کے لیے

پورا صفحہ کھولیں

Ozanimod اور Rasagiline کے لیے مکمل طبی انتظام کی رہنمائی، اضافی نوٹس، شواہد کی تفصیل اور پورے نسخے کا تعامل چیکر کھولنے کے لیے اکاؤنٹ بنائیں اور Pro+ ٹرائل شروع کریں۔

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

ویب پر 7 دن تک Pro+ مفت آزمائیں۔ کارڈ کی ضرورت نہیں۔

اکثر پوچھے جانے والے سوالات

Can I take Ozanimod with Rasagiline?

MediHelp rates the interaction as contraindicated. Ozanimod and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ozanimod is metabolised to active metabolites that inhibit MAO-B, so adding an MAO inhibitor may lead to hypertensive crisis or serotonin toxicity, and labeling contraindicates concurrent use. MAO-B inhibitors may also change exposure to ozanimod active metabolites.

How serious is the interaction between Ozanimod and Rasagiline?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and consider alternative therapy for multiple sclerosis or Parkinson disease. Allow at least 14 days after stopping ozanimod before starting an MAO inhibitor.

What other medicines interact with Rasagiline?

MediHelp also lists interactions of Rasagiline with, for example, Atomoxetine, Brimonidine, Bupropion-naltrexone. The full list is on the Rasagiline page.

MediHelp ایپ میں مکمل مونوگراف، خوراک اور تعامل چیکر

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