Diseases
acetaminophen overdose
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Acetaminophen in overdose can seriously damage the liver. If the damage is severe, a liver transplant may be necessary in order to save someone's life. The antidote to acetaminophen overdose is N-acetylcysteine (NAC). It is most effective when given within eight hours of ingesting acetaminophen.
Symptoms
- nausea
- abdominal pain
- not able to eat or poor appetite
- vomiting
- confusion
Causes
- acetaminophen is primarily metabolized by the liver. too much acetaminophen can overwhelm the way the liver normally functions.
Risk factors
- taking high doses of acetaminophen
Diagnosis
- physical exam.
- history
- lab tests
Medicines used
Frequently asked questions
What is acetaminophen overdose?
Acetaminophen in overdose can seriously damage the liver. If the damage is severe, a liver transplant may be necessary in order to save someone's life. The antidote to acetaminophen overdose is N-acetylcysteine (NAC). It is most effective when given within eight hours of ingesting acetaminophen.
What are the symptoms of acetaminophen overdose?
nausea, abdominal pain, not able to eat or poor appetite, vomiting, confusion
What causes acetaminophen overdose?
acetaminophen is primarily metabolized by the liver. too much acetaminophen can overwhelm the way the liver normally functions.
Which medicines are used for acetaminophen overdose?
acetylcysteine
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